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社区居住的非西班牙裔白人、墨西哥裔美国人和非裔美国男性在下尿路症状严重程度上不存在差异。

Lack of disparity in lower urinary tract symptom severity between community-dwelling non-Hispanic white, Mexican-American, and African-American men.

作者信息

Markland Alayne D, Thompson Ian M, Ankerst Donna P, Higgins Betsy, Kraus Stephen R

机构信息

Division of Gerontology and Geriatric Medicine, Department of Medicine, the University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

Urology. 2007 Apr;69(4):697-702. doi: 10.1016/j.urology.2007.01.024.

Abstract

OBJECTIVES

To determine whether disparities exist in the reporting of lower urinary tract symptoms (LUTS) in non-Hispanic white (NHW), Mexican-American (MA), and African-American (AA) men.

METHODS

Data were collected from a prospective, community-based cohort assembled to study risk factors associated with prostate cancer. Measures included demographics, prostate-specific antigen (PSA), body mass index (BMI), and family history of prostate cancer. Lower urinary tract symptom severity was assessed in 2804 men (1485 NHW, 964 MA, 355 AA) without prostate cancer according to the American Urological Association Symptom Index.

RESULTS

No significant difference (P = 0.998) was seen in the prevalence of moderate or severe LUTS in NHW (34%), MA (34%), and AA (33%) men. No differences were found in either obstructive or irritative symptoms among the three groups. Age, PSA level, BMI, and family history did not affect symptom severity.

CONCLUSIONS

Rates of moderate to severe LUTS symptoms in this cohort were similar to those in other community-based populations of NHW men. Lower rates of moderate or severe symptoms were noted in AA men than previously reported. Mexican-American men had similar degrees of LUTS as the general population, and with their increased risk for diabetes and renal disease, in-depth study of this population is warranted.

摘要

目的

确定非西班牙裔白人(NHW)、墨西哥裔美国人(MA)和非裔美国人(AA)男性在报告下尿路症状(LUTS)方面是否存在差异。

方法

数据收集自一个前瞻性的、基于社区的队列,该队列旨在研究与前列腺癌相关的风险因素。测量指标包括人口统计学特征、前列腺特异性抗原(PSA)、体重指数(BMI)以及前列腺癌家族史。根据美国泌尿外科学会症状指数,对2804名无前列腺癌的男性(1485名NHW、964名MA、355名AA)的下尿路症状严重程度进行了评估。

结果

NHW男性(34%)、MA男性(34%)和AA男性(33%)中,中度或重度LUTS的患病率无显著差异(P = 0.998)。三组在梗阻性或刺激性症状方面均未发现差异。年龄、PSA水平、BMI和家族史均不影响症状严重程度。

结论

该队列中中度至重度LUTS症状的发生率与其他基于社区的NHW男性人群相似。AA男性中中度或重度症状的发生率低于先前报道。墨西哥裔美国男性的LUTS程度与一般人群相似,鉴于他们患糖尿病和肾病的风险增加,有必要对该人群进行深入研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a809/2396510/4678fabd2e3c/nihms-22535-f0001.jpg

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Natural history of benign prostatic hyperplasia.良性前列腺增生的自然病史。
Urology. 2001 Dec;58(6 Suppl 1):5-16; discussion 16. doi: 10.1016/s0090-4295(01)01298-5.

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