Skinner Erin I, Fernandes Myra A
Department of Psychology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada.
Neuropsychologia. 2007 Jun 11;45(10):2163-79. doi: 10.1016/j.neuropsychologia.2007.03.007. Epub 2007 Mar 12.
Dual-process models of recognition memory suggest that two processes contribute to performance: recollection and familiarity. Recent work suggests that the two processes are dissociable at the level of the brain. Here we review 12 studies that used event-related functional magnetic resonance imaging (fMRI), and 21 studies of patients with damage to various brain regions, which examined recollection and familiarity using the 'Remember-Know' (R/K), process dissociation procedure (PDP), or receiver operator characteristic (ROC) memory paradigms, for insights into the neural basis of each process. Results show that recollection and familiarity are characterized by different patterns of brain activity in frontal, parietal, sensory, and medial temporal cortices. Results suggest that recollection and familiarity cannot be dissociated based on confidence levels alone, and that the two processes are not exclusive. Based on these results, we propose a model in which recollection and familiarity can be dissociated in two ways: recruitment of additional brain regions in frontal, medial temporal, and content-specific cortices during recollection, and in variations in coherence of brain networks activated during recollective- or familiarity-based processing.
识别记忆的双过程模型表明，有两个过程对记忆表现有贡献：回忆和熟悉度。最近的研究表明，这两个过程在大脑层面是可分离的。在此，我们回顾了12项使用事件相关功能磁共振成像（fMRI）的研究，以及21项针对不同脑区受损患者的研究，这些研究使用“记得-知道”（R/K）、过程分离程序（PDP）或接收者操作特征（ROC）记忆范式来检验回忆和熟悉度，以深入了解每个过程的神经基础。结果表明，回忆和熟悉度在额叶、顶叶、感觉和内侧颞叶皮质中表现出不同的脑活动模式。结果表明，回忆和熟悉度不能仅基于置信水平来分离，且这两个过程并非相互排斥。基于这些结果，我们提出了一个模型，其中回忆和熟悉度可以通过两种方式分离：回忆过程中额叶、内侧颞叶和特定内容皮质中额外脑区的募集，以及基于回忆或熟悉度的加工过程中激活的脑网络连贯性的变化。
