Fagenholz Peter J, Castillo Carlos Fernández-del, Harris N Stuart, Pelletier Andrea J, Camargo Carlos A
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Ann Epidemiol. 2007 Jul;17(7):491-7. doi: 10.1016/j.annepidem.2007.02.002. Epub 2007 Apr 19.
To examine the epidemiology of hospital admissions for acute pancreatitis in the United States.
We compiled data from the 1988-2003 National Hospital Discharge Survey and analyzed it with respect to patient demographics, hospital type and region, procedures performed, length of hospital stay, and inpatient mortality.
Hospital admissions for acute pancreatitis increased from a 1988 low of 101,000 (95% confidence interval [CI]: 87,000-116,000) to a 2002 peak of 210,000 (95% CI: 186,000-234,000). The corresponding admission rate increased from 0.4 to 0.7 hospitalizations per 1000 U.S. population (p = 0.001). The patients' average age was 53 years, 51% were male, and 23% were black. The hospitalization rate was higher among blacks (0.9; 95% CI, 0.6-1.1) than among whites (0.4; 95% CI, 0.3-0.5). The mean length of stay was 6.9 days and decreased over the study period. Overall mortality was 2%, with increasing age and male gender comprising independent risk factors for death.
The hospitalization rate for acute pancreatitis in the United States is rising and is higher in blacks than in whites. Further research is necessary to identify the cause(s) of increasing pancreatitis admissions, the observed racial disparity, and the cost of these admissions.
研究美国急性胰腺炎住院治疗的流行病学情况。
我们收集了1988 - 2003年全国医院出院调查的数据，并就患者人口统计学特征、医院类型和地区、所实施的手术、住院时间以及住院死亡率进行了分析。
急性胰腺炎的住院人数从1988年的低点101,000例（95%置信区间[CI]：87,000 - 116,000）增加到2002年的峰值210,000例（95%CI：186,000 - 234,000）。相应的住院率从每1000美国人口0.4次住院增加到0.7次住院（p = 0.001）。患者的平均年龄为53岁，51%为男性，23%为黑人。黑人的住院率（0.9；95%CI，0.6 - 1.1）高于白人（0.4；95%CI，0.3 - 0.5）。平均住院时间为6.9天，且在研究期间有所下降。总体死亡率为2%，年龄增长和男性是死亡的独立危险因素。
美国急性胰腺炎的住院率正在上升，且黑人高于白人。有必要进一步研究以确定胰腺炎住院人数增加的原因、观察到的种族差异以及这些住院治疗的费用。
