Görlich M, Heise E
Arch Geschwulstforsch. 1975;45(5):444-52.
Using the method for receptor determination recommended by the EORTC breast, cancer group we found 33.8% of our tissue specimen experimentally estradiol sensitive. No relation could be seen between receptor binding ability of the tumor tissues and lymph node involvement, tumor histology, clinical stages of the disease and menopausal state of the patients, respectively. In most cases primary tumor tissues and tissues of invaded lymph nodes show a corresponding behaviour in relation to estradiol uptake. The differences observed in the effects of various antiestrogenic substances on estradiol binding ability can not be explained at present.
采用欧洲癌症研究与治疗组织（EORTC）乳腺癌研究组推荐的受体检测方法，我们发现33.8%的组织标本对实验性雌二醇敏感。肿瘤组织的受体结合能力与淋巴结受累情况、肿瘤组织学、疾病临床分期以及患者绝经状态之间均未发现相关性。在大多数情况下，原发性肿瘤组织和受累淋巴结组织在雌二醇摄取方面表现出相应的行为。目前尚无法解释各种抗雌激素物质对雌二醇结合能力影响的差异。
