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墨西哥城北部儿童过敏性鼻炎的相关因素。

Factors associated with allergic rhinitis in children from northern Mexico City.

作者信息

Del-Río-Navarro B E, Luna-Pech J A, Berber A, Zepeda-Ortega B, Avila-Castañon L, Del-Río-Chivardi J M, Baeza-Bacab M, Sienra-Monge J J L

机构信息

Department of Allergy and Clinical Immunology, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico.

出版信息

J Investig Allergol Clin Immunol. 2007;17(2):77-84.

Abstract

BACKGROUND

The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire allows users to find factors associated with allergic diseases, but thus far most of the studies on risk factors for allergic diseases have been devoted to asthma and not to rhinitis.

OBJECTIVE

To determine the main factors associated with symptoms of allergic rhinitis and rhinoconjunctivitis in school children and adolescents in northern Mexico City.

PATIENTS AND METHODS

A cross sectional, multicenter survey was conducted in northern Mexico City, in children aged 6-7 and 13-14 years. The survey instrument was the Phase Three B ISAAC questionnaire, which was validated and standardized in Spanish.

RESULTS

There were 4106 6-7-year-olds and 6576 13-14-year-olds. The total prevalence of diagnosis of allergic rhinitis was 4.6%. The prevalence of cumulative and current symptoms of rhinitis was considered high (>29%), but the prevalence of the diagnosis of allergic rhinitis was considered low (ranging from 3.4% to 5.6%). The prevalence of symptoms of rhinitis with conjunctivitis had intermediate values (ranging from 20.3% to 30.2%). Cumulative symptoms of allergic rhinitis, current symptoms of allergic rhinitis, and rhinoconjunctivitis were related to symptoms of current or cumulative asthma, symptoms of current or cumulative atopic eczema, and current use of paracetamol (odds ratio > 1, P < .05).

CONCLUSION

The present results support the concept of rhinitis and asthma as common chronic respiratory diseases, and this study also found a relation between paracetamol use and rhinitis in children.

摘要

背景

儿童哮喘和过敏国际研究(ISAAC)问卷可让使用者找出与过敏性疾病相关的因素,但迄今为止,大多数关于过敏性疾病危险因素的研究都集中在哮喘而非鼻炎上。

目的

确定墨西哥城北部学童和青少年过敏性鼻炎及鼻结膜炎症状的主要相关因素。

患者和方法

在墨西哥城北部对6至7岁和13至14岁的儿童进行了一项横断面多中心调查。调查工具为ISAAC问卷第三阶段B版,该问卷已在西班牙语中得到验证和标准化。

结果

有4106名6至7岁儿童和6576名13至14岁儿童。过敏性鼻炎的诊断总患病率为4.6%。鼻炎累积症状和当前症状的患病率被认为较高(>29%),但过敏性鼻炎的诊断患病率被认为较低(3.4%至5.6%)。伴有结膜炎的鼻炎症状患病率处于中等水平(20.3%至30.2%)。过敏性鼻炎的累积症状、过敏性鼻炎的当前症状以及鼻结膜炎与当前或累积哮喘症状、当前或累积特应性皮炎症状以及当前使用对乙酰氨基酚有关(比值比>1,P<.05)。

结论

目前的结果支持鼻炎和哮喘是常见慢性呼吸道疾病的概念,并且本研究还发现儿童使用对乙酰氨基酚与鼻炎之间存在关联。

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