新生儿疱疹感染的发病率。

The incidence of neonatal herpes infection.

作者信息

Mahnert Nichole, Roberts Scott W, Laibl Vanessa R, Sheffield Jeanne S, Wendel George D

机构信息

Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center, Dallas, TX, USA.

出版信息

Am J Obstet Gynecol. 2007 May;196(5):e55-6. doi: 10.1016/j.ajog.2006.10.911.

DOI:10.1016/j.ajog.2006.10.911

PMID:17466681

Abstract

OBJECTIVE

The incidence of perinatal transmission of neonatal herpes infection has recently been reported at 1 in 3200 births. The main objective of this study was to determine a population-based incidence of neonatal herpes simplex virus infection.

STUDY DESIGN

This was a retrospective chart review of newborn infants presenting with herpes infection established by cerebrospinal fluid polymerase chain reaction or lesion culture between 1999 and 2003. Only infants delivered at our institution were considered to establish a population-based incidence.

RESULTS

Four cases of neonatal herpes infection were identified based on polymerase chain reaction and culture diagnosis. During the study period 78,115 infants were delivered at our institution yielding an incidence of 1 in 20,000 live births.

CONCLUSION

The incidence of neonatal herpes infection at our institution is lower than reported elsewhere. A national surveillance program of neonatal herpes is needed to measure the burden of disease across the United States.

摘要