使用以C-糖苷为中心的策略合成A-E型甘比尔酸亚基。
Synthesis of an A-E gambieric acid subunit with use of a C-glycoside centered strategy.
作者信息
Roberts Scott W, Rainier Jon D
机构信息
Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.
出版信息
Org Lett. 2007 May 24;9(11):2227-30. doi: 10.1021/ol0707970. Epub 2007 May 1.
PMID:17469838
Abstract
This paper describes our synthesis of the A-E subunit of gambieric acid (GA) in addition to the synthesis of the A-ring and the C-E tricycle. The use of an enol ether-olefin RCM strategy to couple the A and C-E subunits and, in the process, generate the B-ring is noteworthy.
摘要
本文描述了我们除了合成冈比亚酸（GA）的A环和C-E三环外，还合成了其A-E亚基。使用烯醇醚-烯烃复分解策略来偶联A和C-E亚基，并在此过程中生成B环，这一点值得注意。
Zotero 插件