Petry Nancy M, Alessi Sheila M, Hanson Tressa
Department of Psychiatry, University of Connecticut Health Center, Farmington, CT 06030, USA.
J Consult Clin Psychol. 2007 Apr;75(2):307-15. doi: 10.1037/0022-006X.75.2.307.
Contingency management (CM) treatments enhance drug abstinence. This study evaluated whether CM also improves quality of life and if these effects are mediated by abstinence. Across 3 independent trials, cocaine abusers in intensive outpatient treatment (n = 387) were randomly assigned to 12 weeks of standard treatment as usual or standard treatment with CM. The Quality Of Life Inventory (QOLI) was administered at baseline and at Months 1, 3, 6, and 9. Changes in QOLI scores over time differed significantly by treatment, with QOLI scores rising over time in CM participants and remaining stable in standard treatment participants. CM participants also achieved greater durations of abstinence, and duration of abstinence was correlated with posttreatment QOLI scores. During-treatment abstinence mediated the relationship between treatment condition and QOLI scores over time.
应急管理（CM）治疗可提高药物戒断率。本研究评估了CM是否还能改善生活质量，以及这些效果是否由戒断介导。在3项独立试验中，强化门诊治疗的可卡因滥用者（n = 387）被随机分配接受为期12周的常规标准治疗或CM标准治疗。在基线以及第1、3、6和9个月时进行生活质量量表（QOLI）评估。随着时间推移，QOLI得分的变化在不同治疗组间存在显著差异，CM组参与者的QOLI得分随时间上升，而标准治疗组参与者的得分保持稳定。CM组参与者的戒断持续时间也更长，且戒断持续时间与治疗后QOLI得分相关。治疗期间的戒断介导了治疗条件与随时间变化的QOLI得分之间的关系。
