来自内生放线菌新种卢氏小单孢菌的抗肿瘤蒽醌类化合物
Antitumor anthraquinones from an endophytic actinomycete Micromonospora lupini sp. nov.
作者信息
Igarashi Yasuhiro, Trujillo Martha E, Martínez-Molina Eustoquio, Yanase Saeko, Miyanaga Satoshi, Obata Takamasa, Sakurai Hiroaki, Saiki Ikuo, Fujita Tsuyoshi, Furumai Tamotsu
机构信息
Biotechnology Research Center, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama, Japan.
出版信息
Bioorg Med Chem Lett. 2007 Jul 1;17(13):3702-5. doi: 10.1016/j.bmcl.2007.04.039. Epub 2007 Apr 19.
Two novel anthraquinones, lupinacidins A (1) and B (2), have been isolated from the culture broth of a new endophytic actinomycete belonging to the genus Micromonospora. Lupinacidins were found to show significant inhibitory effects on the invasion of murine colon 26-L5 carcinoma cells without inhibiting cell growth.
从一种新的小单孢菌属内生放线菌的培养液中分离出两种新型蒽醌类化合物，羽扇豆黄素A（1）和羽扇豆黄素B（2）。发现羽扇豆黄素对小鼠结肠26-L5癌细胞的侵袭具有显著抑制作用，而不抑制细胞生长。
Zotero 插件