Clark Uraina S, Oscar-Berman Marlene, Shagrin Barbara, Pencina Michael
Department of Psychology, Boston University, Boston, MA, USA.
Neuropsychology. 2007 May;21(3):346-62. doi: 10.1037/0894-4105.21.3.346.
This study sought to differentiate alcoholism-related changes in judgments of emotional stimuli from those of other populations in which such changes have been documented. Two sets of visual stimuli, one containing words and the other containing drawings of faces (representing a range of emotional content), were presented to abstinent alcoholic adults with and without Korsakoff's syndrome, as well as to a healthy control group and four groups of patients with other neurobehavioral disorders: Parkinson's disease, schizophrenia, depression, and posttraumatic stress disorder. Participants rated the stimuli according to emotional valence and intensity of emotion. Results implicated bi-hemispheric frontal and subcortical involvement in the abnormalities of emotion identification associated with alcoholism, and they also support the notion of age-related vulnerabilities in conjunction with alcoholism.
本研究旨在区分酒精中毒相关的情绪刺激判断变化与其他已记录有此类变化的人群的变化。向患有和未患有科萨科夫综合征的戒酒成年酗酒者、一个健康对照组以及四组患有其他神经行为障碍(帕金森病、精神分裂症、抑郁症和创伤后应激障碍)的患者呈现了两组视觉刺激,一组包含单词,另一组包含面部图画(代表一系列情绪内容)。参与者根据情绪效价和情绪强度对刺激进行评分。结果表明,双半球额叶和皮质下区域参与了与酒精中毒相关的情绪识别异常,并且它们还支持了与酒精中毒相关的年龄相关易感性的观点。