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慢性阻塞性肺疾病(COPD)患者参加短期肺康复计划后所获得的益处会持续存在吗?

Do the benefits gained using a short-term pulmonary rehabilitation program remain in COPD patients after participation?

作者信息

Karapolat Hale, Atasever Alev, Atamaz Funda, Kirazli Yeşim, Elmas Funda, Erdinç Ertürk

机构信息

Physical Medicine and Rehabilitation Department, Ege University Medical Faculty, 35100 Bornova, Izmir, Turkey.

出版信息

Lung. 2007 Jul-Aug;185(4):221-5. doi: 10.1007/s00408-007-9011-4. Epub 2007 May 9.

Abstract

The aim of this study was to evaluate the short-term benefits of a pulmonary rehabilitation program in chronic obstructive pulmonary disease (COPD) patients. The study was a randomized controlled trial that included 54 mild and moderate COPD patients. Patients were assigned to either an 8-week-long pulmonary rehabilitation program, which consisted of exercise plus education (rehabilitation group), or were controls. All the patients were evaluated at baseline at the completion of the 8th week of the program and one month after the completion of the pulmonary rehabilitation program using five instruments: arterial blood gas analysis, postbronchodilator pulmonary function test, 6-minute walk test (6MWT), Saint George Respiratory Questionnaire (SGRQ), and the dyspnea visual analog scale (VAS) There were no statistically significant differences in the pulmonary functions and pulmonary gas analysis between baseline, discharge (8th week), and the 12th-week visit in both groups (p > 0.05). Rehabilitation resulted in significant improvements in both the VAS and the 6MWT at the 8th week, but by the 12th week all of these improvements had deteriorated. All of the SGRQ domains improved both at the 8th and the 12th week, with a significant difference between the groups (p < 0.05). We conclude that rehabilitation resulted in improvements in exercise capacity, health status, and dyspnea. All of these benefits, however, tend to deteriorate in the first month after rehabilitation. Therefore, it is strongly recommended that all patients with COPD be kept motivated in order to continue with rehabilitation and maintain the benefits gained.

摘要

本研究的目的是评估慢性阻塞性肺疾病(COPD)患者肺康复计划的短期益处。该研究是一项随机对照试验,纳入了54例轻度和中度COPD患者。患者被分配到为期8周的肺康复计划组(包括运动加教育,即康复组)或对照组。使用五种工具在基线、计划第8周结束时以及肺康复计划完成后1个月对所有患者进行评估:动脉血气分析、支气管扩张剂后肺功能测试、6分钟步行试验(6MWT)、圣乔治呼吸问卷(SGRQ)和呼吸困难视觉模拟量表(VAS)。两组在基线、出院时(第8周)和第12周就诊时的肺功能和肺气体分析方面均无统计学显著差异(p>0.05)。康复在第8周时使VAS和6MWT均有显著改善,但到第12周时,所有这些改善都有所恶化。SGRQ的所有领域在第8周和第12周时均有所改善,两组之间存在显著差异(p<0.05)。我们得出结论,康复可改善运动能力、健康状况和呼吸困难。然而,所有这些益处往往在康复后的第一个月内恶化。因此,强烈建议所有COPD患者保持积极性,以便继续进行康复并维持所获得的益处。

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