Zhang Yingchun, van Drongelen Wim, He Bin
Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455.
Appl Phys Lett. 2006;89(22):223903-2239033. doi: 10.1063/1.2398883.
The electrical conductivity value of the human skull is important for biophysics research of the brain. In the present study, the human brain-to-skull conductivity ratio was estimated through in vivo experiments utilizing intra-cranial electrical stimulation in two epilepsy patients. A realistic geometry inhomogeneous head model including the implanted silastic grids was constructed with the aid of the finite element method, and used to estimate the conductivity ratio. Averaging over 49 sets of measurements, the mean value and standard deviation of the brain-to-skull conductivity ratio were found to be 18.7 and 2.1, respectively.
人类头骨的电导率值对于大脑的生物物理学研究很重要。在本研究中,通过对两名癫痫患者进行颅内电刺激的体内实验,估算了人脑与头骨的电导率之比。借助有限元方法构建了一个包含植入的硅橡胶网格的真实几何非均匀头部模型,并用于估算电导率之比。对49组测量值进行平均后,发现人脑与头骨电导率之比的平均值和标准差分别为18.7和2.1。