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体重指数与糖尿病、高血压和血脂异常的关系:两项全国性调查数据的比较。

The relationship of body mass index to diabetes mellitus, hypertension and dyslipidaemia: comparison of data from two national surveys.

作者信息

Bays H E, Chapman R H, Grandy S

机构信息

Louisville Metabolic and Atherosclerosis Research Center, Louisville, KY 40213, USA.

出版信息

Int J Clin Pract. 2007 May;61(5):737-47. doi: 10.1111/j.1742-1241.2007.01336.x.

Abstract

The objectives of this study were to explore the relation between body mass index (BMI) and prevalence of diabetes mellitus, hypertension and dyslipidaemia; examine BMI distributions among patients with these conditions; and compare results from two national surveys. The Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD) 2004 screening questionnaire (mailed survey) and the National Health and Nutrition Examination Surveys (NHANES) 1999-2002 (interview, clinical and laboratory data) were conducted in nationally representative samples>or=18 years old. Responses were received from 127,420 of 200,000 households (64%, representing 211,097 adults) for SHIELD, and 4257 participants for NHANES. Prevalence of diabetes mellitus, hypertension and dyslipidaemia was estimated within BMI categories, as was distribution of BMI levels among individuals with these diseases. Mean BMI was 27.8 kg/m2 for SHIELD and 27.9 kg/m2 for NHANES. Increased BMI was associated with increased prevalence of diabetes mellitus, hypertension and dyslipidaemia in both studies (p<0.001). For each condition, approximately [corrected] 75% or more [corrected] of patients had BMI>or=25 kg/m2. Estimated prevalence of diabetes mellitus and hypertension was similar in both studies, while dyslipidaemia was substantially higher in NHANES than SHIELD. In both studies, prevalence of diabetes mellitus, hypertension and dyslipidaemia occurred across all ranges of BMI, but increased with higher BMI. However, not all overweight or obese patients had these metabolic diseases and not all with these conditions were overweight or obese. Except for dyslipidaemia prevalence, SHIELD was comparable with NHANES. Consumer panel surveys may be an alternative method to collect data on the relationship of BMI and metabolic diseases.

摘要

本研究的目的是探讨体重指数(BMI)与糖尿病、高血压和血脂异常患病率之间的关系;研究这些疾病患者的BMI分布情况;并比较两项全国性调查的结果。针对年龄≥18岁具有全国代表性的样本开展了2004年糖尿病风险因素早期评估与管理促进研究(SHIELD)筛查问卷(邮寄调查)以及1999 - 2002年国家健康与营养检查调查(NHANES,访谈、临床及实验室数据)。SHIELD从20万户家庭中的127,420户(64%,代表211,097名成年人)收到了回复,NHANES有4257名参与者。在不同BMI类别中估算了糖尿病、高血压和血脂异常的患病率,以及这些疾病患者的BMI水平分布。SHIELD的平均BMI为27.8kg/m²,NHANES为27.9kg/m²。两项研究中,BMI升高均与糖尿病、高血压和血脂异常患病率增加相关(p<0.001)。对于每种疾病,约75%或更多患者的BMI≥25kg/m²。两项研究中糖尿病和高血压的估算患病率相似,而NHANES中血脂异常的患病率显著高于SHIELD。在两项研究中,糖尿病、高血压和血脂异常的患病率在所有BMI范围内均有发生,但随BMI升高而增加。然而,并非所有超重或肥胖患者都患有这些代谢疾病,也并非所有患有这些疾病的患者都超重或肥胖。除血脂异常患病率外,SHIELD与NHANES具有可比性。消费者小组调查可能是收集BMI与代谢疾病关系数据的另一种方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b3/1890993/6c3a5e4046b9/ijcp0061-0737-f1.jpg

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