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1999 - 2010年美国国家健康和营养检查调查(NHANES)中按肥胖水平划分的成人心血管疾病风险因素趋势

Trends in cardiovascular disease risk factors by obesity level in adults in the United States, NHANES 1999-2010.

作者信息

Saydah Sharon, Bullard Kai McKeever, Cheng Yiling, Ali Mohammed K, Gregg Edward W, Geiss Linda, Imperatore Giuseppina

机构信息

Centers for Disease Control and Prevention, National Center for Health Promotion and Disease Prevention, Division of Diabetes Translation, Hyattsville, MD, USA.

出版信息

Obesity (Silver Spring). 2014 Aug;22(8):1888-95. doi: 10.1002/oby.20761. Epub 2014 Apr 15.

Abstract

OBJECTIVE

To assess whether trends in cardiovascular disease (CVD) risk factors by among overweight and obese US adults have improved.

METHODS

The study included 10,568 adults 18 years and older who participated in National Health and Nutrition Examination Survey 1999-2010. CVD risk factors included diabetes (self-reported diagnosis, glycated hemoglobin ≥6.5%, or fasting plasma glucose ≥126mg/dl), hypertension (treatment or blood pressure ≥140/90 mmHg), dyslipidemia (treatment or non-HDL cholesterol ≥160 mg/dl), and smoking (self-report or cotinine levels ≥10 ng/ml). The prevalence and temporal trends of CVD risk factors for each BMI group were estimated.

RESULTS

In 2007-2010, the prevalence of diabetes, hypertension, and dyslipidemia was highest among obese (18.5%, 35.7%, 49.7%, respectively) followed by overweight (8.2%, 26.4%, 44.2%, respectively) and normal weight adults (5.4%, 19.8%, 28.6%, respectively). Smoking exposure was highest among normal weight (29.8%) followed by overweight (24.8%) and obese adults (24.6%). From 1999-2002 to 2007-2010, untreated hypertension decreased among obese and overweight adults and untreated dyslipidemia decreased for all weight groups. There were no significant temporal changes in smoking across BMI groups.

CONCLUSIONS

Despite decreases in untreated risk factors, it is important to improve the CVD risk profile of overweight and obese US adults.

摘要

目的

评估美国超重和肥胖成年人中心血管疾病(CVD)危险因素的趋势是否有所改善。

方法

该研究纳入了10568名18岁及以上参与1999 - 2010年美国国家健康与营养检查调查的成年人。心血管疾病危险因素包括糖尿病(自我报告诊断、糖化血红蛋白≥6.5%或空腹血糖≥126mg/dl)、高血压(接受治疗或血压≥140/90 mmHg)、血脂异常(接受治疗或非高密度脂蛋白胆固醇≥160 mg/dl)以及吸烟(自我报告或可替宁水平≥10 ng/ml)。估计了每个体重指数(BMI)组中心血管疾病危险因素的患病率和时间趋势。

结果

在2007 - 2010年,糖尿病、高血压和血脂异常的患病率在肥胖成年人中最高(分别为18.5%、35.7%、49.7%),其次是超重成年人(分别为8.2%、26.4%、44.2%)和正常体重成年人(分别为5.4%、19.8%、28.6%)。吸烟暴露率在正常体重成年人中最高(29.8%),其次是超重成年人(24.8%)和肥胖成年人(24.6%)。从1999 - 2002年到2007 - 2010年,肥胖和超重成年人中未经治疗的高血压有所下降,所有体重组中未经治疗的血脂异常均有所下降。各BMI组的吸烟情况在时间上没有显著变化。

结论

尽管未经治疗的危险因素有所减少,但改善美国超重和肥胖成年人的心血管疾病风险状况仍很重要。

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