用于再生医学的脂肪来源干细胞。
Adipose-derived stem cells for regenerative medicine.
作者信息
Gimble Jeffrey M, Katz Adam J, Bunnell Bruce A
机构信息
Stem Cell Biology Laboratory and Clinical Nutrition Research Unit, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA.
出版信息
Circ Res. 2007 May 11;100(9):1249-60. doi: 10.1161/01.RES.0000265074.83288.09.
Abstract
The emerging field of regenerative medicine will require a reliable source of stem cells in addition to biomaterial scaffolds and cytokine growth factors. Adipose tissue represents an abundant and accessible source of adult stem cells with the ability to differentiate along multiple lineage pathways. The isolation, characterization, and preclinical and clinical application of adipose-derived stem cells (ASCs) are reviewed in this article.
摘要
除了生物材料支架和细胞因子生长因子外，再生医学这一新兴领域还需要可靠的干细胞来源。脂肪组织是成体干细胞的丰富且易获取的来源，具有沿多种谱系途径分化的能力。本文对脂肪来源干细胞（ASC）的分离、表征以及临床前和临床应用进行了综述。
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