Facile quantification of lesions derived from 2'-deoxyguanosine in DNA.
作者信息
Xue Liang, Greenberg Marc M
机构信息
Department of Chemistry, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.
出版信息
J Am Chem Soc. 2007 Jun 6;129(22):7010-1. doi: 10.1021/ja072174n. Epub 2007 May 11.
Abstract
摘要
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Use of fluorescence sensors to determine that 2-deoxyribonolactone is the major alkali-labile deoxyribose lesion produced in oxidatively damaged DNA.使用荧光传感器确定2-脱氧核糖内酯是氧化损伤DNA中产生的主要碱不稳定脱氧核糖损伤。
Angew Chem Int Ed Engl. 2007;46(4):561-4. doi: 10.1002/anie.200603454.
2
Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells.氧化性DNA损伤的遗传效应：猴肾细胞中咪唑环开环的甲酰胺基嘧啶（Fapy损伤）和8-氧代嘌呤的比较诱变
Nucleic Acids Res. 2006 May 5;34(8):2305-15. doi: 10.1093/nar/gkl099. Print 2006.
3
Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products.鸟嘌呤氧化产物的形成机制、遗传毒性及突变
Chem Res Toxicol. 2006 Apr;19(4):491-505. doi: 10.1021/tx0600043.
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Selective detection of 2-deoxyribonolactone in DNA.DNA中2-脱氧核糖内酯的选择性检测。
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Spermine participates in oxidative damage of guanosine and 8-oxoguanosine leading to deoxyribosylurea formation.精胺参与鸟苷和8-氧代鸟苷的氧化损伤，导致脱氧核糖脲的形成。
J Am Chem Soc. 2004 Aug 11;126(31):9540-1. doi: 10.1021/ja047981q.
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Oxidation of 5-hydroxy-2'-deoxyuridine into isodialuric acid, dialuric acid, and hydantoin products.5-羟基-2'-脱氧尿苷氧化为异二脲酸、二脲酸和乙内酰脲产物。
J Am Chem Soc. 2004 Jun 2;126(21):6548-9. doi: 10.1021/ja049438f.
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Are we sure we know how to measure 8-oxo-7,8-dihydroguanine in DNA from human cells?我们确定知道如何测量人类细胞DNA中的8-氧代-7,8-二氢鸟嘌呤吗？
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In vitro and in vivo effects of oxidative damage to deoxyguanosine.脱氧鸟苷氧化损伤的体外和体内效应
Biochem Soc Trans. 2004 Feb;32(Pt 1):46-50. doi: 10.1042/bst0320046.
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Oxidative damage to DNA: formation, measurement and biochemical features.DNA的氧化损伤：形成、测量及生化特征
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