Shorter Barbara, Lesser Martin, Moldwin Robert M, Kushner Leslie
Department of Nutrition, C. W. Post Campus of Long Island University, Brookville, New York, USA.
J Urol. 2007 Jul;178(1):145-52. doi: 10.1016/j.juro.2007.03.020. Epub 2007 May 11.
Anecdotal evidence suggests that patients with painful bladder syndrome/interstitial cystitis report symptom exacerbation after consuming particular foods, beverages and/or supplements. We determined the prevalence of the effect of comestibles on painful bladder syndrome/interstitial cystitis symptoms and identified particular comestible items more likely to affect such symptoms.
A validated questionnaire designed to detect whether food, beverages and/or supplements have an effect on bladder symptoms was administered to 104 patients meeting National Institute for Diabetes and Digestive and Kidney Diseases criteria for interstitial cystitis. In addition to answering general questions about the effect of comestibles on painful bladder syndrome/interstitial cystitis symptoms, subjects were asked to indicate whether each of 175 individual items worsened, improved or had no effect on symptoms. Each response was numerically scored on a scale of -2 to 2 and mean values were generated for each comestible item.
Of the surveyed patients with painful bladder syndrome/interstitial cystitis 90.2% indicated that the consumption of certain foods or beverages caused symptom exacerbation. There was no correlation between allergies and the effect of comestibles on symptoms. Patients who reported that specific foods worsened symptoms tended to have higher O'Leary-Sant interstitial cystitis symptom index and problem index, and/or pelvic pain and urgency/frequency patient symptom scale scores. A total of 35 comestible items had a mean score of lower than -1.0, including caffeinated, carbonated and alcoholic beverages, certain fruits and juices, artificial sweeteners and spicy foods.
There is a large cohort of patients with painful bladder syndrome/interstitial cystitis in whom symptoms are exacerbated by the ingestion of specific comestibles. The most frequently reported and most bothersome comestibles were coffee, tea, soda, alcoholic beverages, citrus fruits and juices, artificial sweeteners and hot pepper.
轶事证据表明，膀胱疼痛综合征/间质性膀胱炎患者在食用特定食物、饮料和/或补充剂后症状会加重。我们确定了食物对膀胱疼痛综合征/间质性膀胱炎症状影响的发生率，并确定了更可能影响此类症状的特定食物项目。
向104名符合美国国立糖尿病、消化和肾脏疾病研究所间质性膀胱炎标准的患者发放一份经过验证的问卷，以检测食物、饮料和/或补充剂是否对膀胱症状有影响。除了回答关于食物对膀胱疼痛综合征/间质性膀胱炎症状影响的一般问题外，受试者还被要求指出175种单独项目中的每一种对症状是加重、改善还是没有影响。每个回答在-2至2的量表上进行数字评分，并为每个食物项目生成平均值。
在接受调查的膀胱疼痛综合征/间质性膀胱炎患者中，90.2%表示食用某些食物或饮料会导致症状加重。过敏与食物对症状的影响之间没有相关性。报告特定食物会加重症状的患者往往具有较高的奥利里-桑特间质性膀胱炎症状指数和问题指数，和/或盆腔疼痛及尿急/尿频患者症状量表评分。共有35种食物项目的平均得分低于-1.0，包括含咖啡因的饮料、碳酸饮料和酒精饮料、某些水果和果汁、人工甜味剂和辛辣食物。
有一大群膀胱疼痛综合征/间质性膀胱炎患者，其症状因摄入特定食物而加重。最常报告且最令人烦恼的食物是咖啡、茶、汽水、酒精饮料、柑橘类水果和果汁、人工甜味剂和辣椒。
