Reinhard M J, Hinkin C H, Barclay T R, Levine A J, Marion S, Castellon S A, Longshore D, Newton T, Durvasula R S, Lam M N, Myers H
Addict Behav. 2007 Dec;32(12):2727-36. doi: 10.1016/j.addbeh.2007.04.006. Epub 2007 Apr 14.
While it has long been recognized that self-reported drug use may be at variance with objectively obtained evidence such as urine toxicology assays, few studies have explored the behavioral correlates of such discrepancies. Here we compared self-reported and objective measures of stimulant drug use for 162 HIV infected individuals and identified a sub-group with discrepancies between data obtained via the two methods. Results showed poorer neurocognitive performance (attention, learning/memory) and lower medication adherence rates for the discrepant group as compared to those who either acknowledged their drug use or accurately denied recent stimulant use. Using the Millon Clinical Multiaxial Inventory-III, it was also found that those in the discrepant group were more hesitant to reveal psychopathology. Comparisons of self-reported and objectively measured medication adherence data are also discussed.
长期以来，人们一直认识到自我报告的药物使用情况可能与客观获得的证据（如尿液毒理学检测）存在差异，但很少有研究探讨这种差异的行为相关性。在此，我们比较了162名感染艾滋病毒个体的自我报告和兴奋剂药物使用的客观测量结果，并确定了一个在两种方法获得的数据之间存在差异的亚组。结果显示，与那些承认使用药物或准确否认近期使用兴奋剂的人相比，差异组的神经认知表现（注意力、学习/记忆）较差，药物依从率较低。使用米隆临床多轴问卷第三版还发现，差异组的人在揭示精神病理学方面更加犹豫。还讨论了自我报告和客观测量的药物依从性数据的比较。
