Seracchioli R, Poggioli G, Pierangeli F, Manuzzi L, Gualerzi B, Savelli L, Remorgida V, Mabrouk M, Venturoli S
Center of Reconstructive Pelvic Endo-surgery, Reproductive Medicine Unit, S.Orsola Hospital, University of Bologna, Bologna, Italy.
BJOG. 2007 Jul;114(7):889-95. doi: 10.1111/j.1471-0528.2007.01363.x. Epub 2007 May 15.
The aim of this study was to assess the long-term outcome of treating severely symptomatic women with deep infiltrating intestinal endometriosis by laparoscopic segmental rectosigmoid resection. Detailed intraoperative and postoperative records and questionnaires (preoperatively, 1 month postoperatively and every 6 months for 3 years) were collected from 22 women. The estimated blood loss during surgery was 290 +/- 162 ml (range 180-600), and average hospital stay was 8 days (range 6-19). One woman required blood transfusion after surgery. Two cases were converted to laparotomy. One woman had early dehiscence of the anastomosis. Six months after surgery, there was a significant reduction of symptom scores (greater than 50% for most types of pain) related to intestinal localisation of endometriosis (P < 0.05). Score improvements were maintained during the whole period of follow up. Noncyclic pelvic pain scores showed significant reductions (P < 0.05) after 6 and 12 months, but there was a high recurrence rate later. Dysmenorrhoea and dyspareunia improved in 18/21 and 14/18 women with preoperative symptoms, respectively. Constipation, diarrhoea and rectal bleeding improved in all affected women for the whole period of follow up. Laparoscopic segmental rectosigmoid resection seems safe and effective in women with deep infiltrating colorectal endometriosis resulting in significant reductions in painful and dysfunctional symptoms associated with deep bowel involvement.
本研究的目的是评估通过腹腔镜乙状结肠直肠节段切除术治疗有严重症状的深部浸润性肠道子宫内膜异位症女性的长期疗效。收集了22名女性详细的术中及术后记录和问卷(术前、术后1个月以及3年中每6个月一次)。手术中的估计失血量为290±162毫升(范围180 - 600),平均住院时间为8天(范围6 - 19)。一名女性术后需要输血。2例转为开腹手术。一名女性出现吻合口早期裂开。术后6个月,与子宫内膜异位症肠道定位相关的症状评分显著降低(大多数类型的疼痛降低超过50%)(P < 0.05)。在整个随访期间评分改善情况得以维持。非周期性盆腔疼痛评分在6个月和12个月后显著降低(P < 0.05),但后期复发率较高。术前有痛经和性交困难症状的女性中,分别有18/21和14/18得到改善。在整个随访期间,所有受影响女性的便秘、腹泻和直肠出血情况均有改善。对于因深部浸润性结直肠子宫内膜异位症导致与深部肠道受累相关的疼痛和功能障碍症状显著减轻的女性,腹腔镜乙状结肠直肠节段切除术似乎是安全有效的。