Feltham M H, Wong R, Wolfe R, Stapleton F
Mark Feltham Optometrists, London Circuit, Canberra, Australian Capital Territory, Australia.
Eye (Lond). 2008 Sep;22(9):1117-23. doi: 10.1038/sj.eye.6702856. Epub 2007 May 18.
To investigate factors affecting refractive outcome following LASIK for myopia.
Six hundred and seventy-four consecutive uncomplicated myopic LASIK surgeries, performed by a single surgeon, either using the Technolas 217 planoscan (n=372) or the NIDEK EC 5000 (n=302), were evaluated. Stratified random sampling was used to match the groups for refractive error, patient age, and gender. The final analysis included 302 patients from each treatment group. Conditions were identical for both surgeries, and pre-operative refractive errors were between -1.00 and -14.00 DS and <-1.50 DC. Refractive success was defined as -0.50 to +0.50 DS of the targeted refraction measured 3 months after surgery. A stepwise logistical regression analysis was used to determine variables associated with refractive failure.
A successful refractive outcome was achieved in 78% (235/302) of surgeries using the Technolas laser and in 88% (266/302) using the NIDEK laser. Predictor variables for not achieving refractive success were pre-operative refractive error of above -5.00 DS, age more than 40 years, and surgery performed with the Technolas laser.
Both the Technolas 217 and the NIDEK EC-5000 excimer lasers achieve a successful refractive outcome in the majority of cases. However, patient and surgical factors can influence refractive outcome.
研究影响近视患者准分子激光原位角膜磨镶术(LASIK)屈光结果的因素。
评估由单一外科医生实施的674例连续无并发症的近视LASIK手术,其中使用Technolas 217准分子激光仪的有372例,使用NIDEK EC 5000准分子激光仪的有302例。采用分层随机抽样使两组在屈光不正、患者年龄和性别方面相匹配。最终分析纳入每个治疗组的302例患者。两种手术的条件相同,术前屈光不正范围为-1.00至-14.00屈光度(DS)且散光小于-1.50屈光度(DC)。屈光成功定义为术后3个月测量的目标屈光度在-0.50至+0.50 DS之间。采用逐步逻辑回归分析确定与屈光失败相关的变量。
使用Technolas激光的手术中有78%(235/302)屈光结果成功,使用NIDEK激光的手术中有88%(266/302)屈光结果成功。未实现屈光成功的预测变量为术前屈光不正超过-5.00 DS、年龄超过40岁以及使用Technolas激光进行手术。
Technolas 217和NIDEK EC - 5000准分子激光在大多数情况下均能取得成功的屈光结果。然而,患者和手术因素会影响屈光结果。