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确定放射治疗的碳离子剂量:海德堡方法。

Specifying carbon ion doses for radiotherapy: the heidelberg approach.

作者信息

Jäkel Oliver, Schulz-Ertner Daniela, Debus Jürgen

机构信息

German Cancer Research Center (DKFZ), Dep. Medical Physics in Radiation Therapy (E040).

出版信息

J Radiat Res. 2007;48 Suppl A:A87-95. doi: 10.1269/jrr.48.a87.

DOI:10.1269/jrr.48.a87
PMID:17513904
Abstract

There are currently no guidelines for prescribing and reporting radiation therapy (RT) with ion beams. In this paper an overview over some technical aspects and their implication on ion RT are reported. This includes a discussion of the difference in the treatment planning systems currently used for active and passive beam shaping systems, aspects of patient positioning and target definition and dose prescription. Special emphasis is put on the questions arising from the use of the beam scanning methods in combination with biological treatment plan optimization, which is used in the German heavy ion therapy facility at GSI and will also be introduced at the hospital based facility in Heidelberg. Furthermore, the Heidelberg approach for the clinical dose prescription is compared with the methods developed at HIMAC in Chiba, Japan.

摘要

目前尚无关于离子束放射治疗(RT)的处方和报告指南。本文报告了一些技术方面及其对离子放射治疗的影响的概述。这包括对当前用于主动和被动束流整形系统的治疗计划系统差异的讨论、患者定位和靶区定义以及剂量处方等方面。特别强调了与生物治疗计划优化相结合使用束流扫描方法所产生的问题,这种方法在德国GSI的重离子治疗设施中使用,也将在海德堡的医院设施中引入。此外,还将海德堡的临床剂量处方方法与日本千叶市HIMAC开发的方法进行了比较。

相似文献

1
Specifying carbon ion doses for radiotherapy: the heidelberg approach.确定放射治疗的碳离子剂量:海德堡方法。
J Radiat Res. 2007;48 Suppl A:A87-95. doi: 10.1269/jrr.48.a87.
2
Recent innovations in carbon-ion radiotherapy.碳离子放疗的最新进展。
J Radiat Res. 2010;51(4):385-92. doi: 10.1269/jrr.10028.
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Heavy ion therapy: status and perspectives.重离子治疗:现状与展望。
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Treatment planning for carbon ion radiotherapy in Germany: review of clinical trials and treatment planning studies.德国碳离子放射治疗的治疗计划:临床试验与治疗计划研究综述
Radiother Oncol. 2004 Dec;73 Suppl 2:S86-91. doi: 10.1016/s0167-8140(04)80022-7.
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Mapping of RBE-weighted doses between HIMAC- and LEM-Based treatment planning systems for carbon ion therapy.在碳离子治疗中,基于 HIMAC 和 LEM 的治疗计划系统之间的 RBE 加权剂量的映射。
Int J Radiat Oncol Biol Phys. 2012 Nov 1;84(3):854-60. doi: 10.1016/j.ijrobp.2012.01.038. Epub 2012 Apr 6.
6
Treatment planning for scanned ion beams.扫描离子束的治疗计划
Radiother Oncol. 2004 Dec;73 Suppl 2:S80-5. doi: 10.1016/s0167-8140(04)80021-5.
7
Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy.用于重离子放射治疗的HIMAC临床照射系统的生物物理特性
Int J Radiat Oncol Biol Phys. 1999 Apr 1;44(1):201-10. doi: 10.1016/s0360-3016(98)00544-6.
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New accelerator facility for carbon-ion cancer-therapy.用于碳离子癌症治疗的新型加速器设施。
J Radiat Res. 2007;48 Suppl A:A43-54. doi: 10.1269/jrr.48.a43.
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Carbon ion radiotherapy for chordomas and low-grade chondrosarcomas of the skull base. Results in 67 patients.碳离子放疗治疗颅底脊索瘤和低级别软骨肉瘤。67例患者的治疗结果。
Strahlenther Onkol. 2003 Sep;179(9):598-605. doi: 10.1007/s00066-003-1120-2.
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Radiotherapy systems using proton and carbon beams.使用质子束和碳离子束的放射治疗系统。
Bull Mem Acad R Med Belg. 2008;163(10-12):471-8; discussion 479-80.

引用本文的文献

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Determining RBE for development of lung fibrosis induced by fractionated irradiation with carbon ions utilizing fibrosis index and high-LET BED model.利用纤维化指数和高传能线密度生物等效剂量(LET BED)模型确定碳离子分次照射诱导肺纤维化的相对生物效应(RBE)
Clin Transl Radiat Oncol. 2018 Nov 2;14:25-32. doi: 10.1016/j.ctro.2018.10.005. eCollection 2019 Jan.
2
Particle therapy of moving targets-the strategies for tumour motion monitoring and moving targets irradiation.移动靶标的粒子治疗——肿瘤运动监测与移动靶标照射策略
Br J Radiol. 2016 Oct;89(1066):20150275. doi: 10.1259/bjr.20150275. Epub 2016 Jul 19.
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Non-randomized therapy trial to determine the safety and efficacy of heavy ion radiotherapy in patients with non-resectable osteosarcoma.
非随机治疗试验,以确定不可切除骨肉瘤患者重离子放疗的安全性和有效性。
BMC Cancer. 2010 Mar 12;10:96. doi: 10.1186/1471-2407-10-96.