不同体重女性的基础代谢率变异性。

BMR variability in women of different weight.

作者信息

Marra Maurizio, Pasanisi Fabrizio, Montagnese Concetta, De Filippo Emilia, De Caprio Carmela, de Magistris Lanfranca, Contaldo Franco

机构信息

Interuniversity Center for Obesity and Eating Disorders, Department of Clinical and Experimental Medicine, Federico II University, 80131 Naples, Italy.

出版信息

Clin Nutr. 2007 Oct;26(5):567-72. doi: 10.1016/j.clnu.2007.03.006. Epub 2007 May 22.

DOI:10.1016/j.clnu.2007.03.006

PMID:17517450

Abstract

BACKGROUND & AIMS: Non-exercise activity thermogenesis (NEAT) and substrate oxidation are significant components of Energy Balance; their regulation may be modulated according to nutritional status and their impairment has been advocated as a factor facilitating the development of excess body fat.

METHODS

In this study body composition, resting metabolic rate (RMR), fidgeting as a component of NEAT and respiratory quotient (RQ), an index of preferential substrate oxidation, have been evaluated in 80 young women: 20 restrictive anorexia nervosa (rAN: BMI 15.1+/-1.6 kg/m(2)); 20 constitutional leanness (CL: BMI 17.2+/-1.0); 20 obese patients (Ob: BMI 43.8+/-10.0) and 20 controls (CTR: BMI 21.7+/-2.4).

RESULTS

Fat free mass, fat mass and RMR progressively increased from rAN to Ob (p < 0.05). Fidgeting was higher in CL (67.2+/-27.2 kcal; p < 0.05) than in the other groups. Lipid oxidation, evaluated with RQ showed a negative correlation with fidgeting in CL (r=-0.433; p<0.05) and positive in Ob (r=0.572; p<0.05) and in rAN (r=0.434; p<0.05).

CONCLUSION

Our findings support the regulatory function of NEAT, its protective role to prevent excess body fat accumulation and its positive relation with fat oxidation in CL.

摘要

背景与目的

非运动活动产热（NEAT）和底物氧化是能量平衡的重要组成部分；它们的调节可能会根据营养状况进行调整，并且它们的受损被认为是促进体内脂肪过多积累的一个因素。

方法

在本研究中，对80名年轻女性的身体成分、静息代谢率（RMR）、作为NEAT组成部分的坐立不安程度以及呼吸商（RQ，优先底物氧化的指标）进行了评估：20名患有神经性厌食症的节食者（rAN：体重指数15.1±1.6kg/m²）；20名体质偏瘦者（CL：体重指数17.2±1.0）；20名肥胖患者（Ob：体重指数43.8±10.0）和20名对照组（CTR：体重指数21.7±2.4）。

结果

从rAN组到Ob组，去脂体重、脂肪量和RMR逐渐增加（p<0.05）。CL组的坐立不安程度（67.2±27.2千卡；p<0.05）高于其他组。用RQ评估的脂质氧化在CL组与坐立不安程度呈负相关（r=-0.433；p<0.05），在Ob组呈正相关（r=0.572；p<0.05），在rAN组也呈正相关（r=0.434；p<0.05）。