Veling Wim, Selten Jean-Paul, Susser Ezra, Laan Winfried, Mackenbach Johan P, Hoek Hans W
Parnassia Psychiatric Institute, The Hague, The Netherlands.
Int J Epidemiol. 2007 Aug;36(4):761-8. doi: 10.1093/ije/dym085. Epub 2007 May 21.
It is well established now that the incidence of schizophrenia is extremely high for several ethnic minority groups in western Europe, but there is considerable variation among groups. We investigated whether the increased risk among these groups depends upon the degree to which they perceive discrimination based on race or ethnicity.
We studied the incidence of psychotic disorders over 7 years in The Hague, a city with a large and diverse population of ethnic minorities. To compare the incidence of schizophrenic disorders (DSM IV: schizophrenia, schizophreniform disorder, schizoaffective disorder) in each ethnic minority group with the incidence in native Dutch, we computed incidence rate ratios (IRRs). Based on a population study and on rates of reported incidents of discrimination in The Hague, the degree of perceived discrimination of ethnic minority groups was rated: high (Morocco), medium (Netherlands-Antilles, Surinam and 'other non-western countries'), low (Turkey) or very low ('western or westernized countries').
The age- and gender-adjusted IRRs of schizophrenic disorders for ethnic minority groups exposed to high, medium, low, and very low discrimination were 4.00 (95% CI 3.00-5.35), 1.99 (1.58-2.51), 1.58 (1.10-2.27), and 1.20 (0.81-1.90), respectively. When not only schizophrenic, but all psychotic disorders were included in the analysis, the results were similar.
These results suggest that discrimination perceived by ethnic minority groups in western Europe, or some factor closely related to it, may contribute to their increased risk of schizophrenia.
目前已充分证实,西欧几个少数民族群体中精神分裂症的发病率极高,但不同群体之间存在相当大的差异。我们调查了这些群体中患病风险增加是否取决于他们感知到的基于种族或族裔的歧视程度。
我们研究了海牙市7年内精神疾病的发病率,该市有大量不同的少数民族人口。为了比较每个少数民族群体中精神分裂症(《精神疾病诊断与统计手册》第四版:精神分裂症、分裂样障碍、分裂情感性障碍)的发病率与荷兰本土人群的发病率,我们计算了发病率比(IRR)。基于一项人口研究以及海牙市报告的歧视事件发生率,对少数民族群体感知到的歧视程度进行了评级:高(摩洛哥)、中(荷属安的列斯群岛、苏里南和“其他非西方国家”)、低(土耳其)或极低(“西方或西方化国家”)。
遭受高、中、低和极低歧视的少数民族群体中,经年龄和性别调整后的精神分裂症发病率比分别为4.00(95%置信区间3.00 - 5.35)、1.99(1.58 - 2.51)、1.58(1.10 - 2.27)和1.20(0.81 - 1.90)。当分析中不仅包括精神分裂症,还包括所有精神疾病时,结果相似。
这些结果表明,西欧少数民族群体感知到的歧视或与之密切相关的某些因素,可能导致他们患精神分裂症的风险增加。