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[药物的鞘内持续给药。麻醉学与重症监护中的特殊情况]

[Continuous intrathecal administration of medication. Special features in anaesthesiology and intensive care].

作者信息

Felleiter P, Lierz P

机构信息

Abt. für Intensivmedizin, Schweizer Paraplegiker-Zentrum Nottwil, 6207 Nottwil, Schweiz.

出版信息

Anaesthesist. 2007 Aug;56(8):822-7. doi: 10.1007/s00101-007-1204-y.

DOI:10.1007/s00101-007-1204-y
PMID:17520226
Abstract

In anaesthesiological and intensive care practice patients are increasingly being treated with implanted medication pumps. Basic knowledge on the special aspects of this form of therapy is therefore important. During the preanasthesiology visit, information on the pump, the intrathecal catheter, type and dosage of the medication as well as the next scheduled refilling must be collected and documented. Needle punctures near the pump and the catheter must be avoided. During intensive care treatment any possible interaction and overdosing or underdosing of the intrathecally administered medication must be considered. Information on the schedule and punctual organisation of refilling are important to avoid complications.

摘要

在麻醉学和重症监护实践中,越来越多的患者接受植入式药物泵治疗。因此,了解这种治疗形式的特殊方面的基本知识很重要。在麻醉前访视期间,必须收集并记录有关泵、鞘内导管、药物类型和剂量以及下次预定补充药物的信息。必须避免在泵和导管附近进行针刺。在重症监护治疗期间,必须考虑鞘内给药的任何可能的相互作用以及用药过量或不足。关于补充药物的时间表和准时安排的信息对于避免并发症很重要。

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[Selected interventional methods for the treatment of chronic pain : part 2: regional anesthetic techniques close to the spinal cord and neuromodulative methods].[慢性疼痛治疗的选定介入方法:第2部分:脊髓附近区域麻醉技术和神经调节方法]
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本文引用的文献

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Intrathecal baclofen for the treatment of intractable spasticity of spine or brain etiology.鞘内注射巴氯芬治疗脊柱或脑部病因所致难治性痉挛。
Neuromodulation. 2000 Apr;3(2):75-81. doi: 10.1046/j.1525-1403.2000.00075.x.
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[Continuous administration of opiates with implantable drug delivery systems in patients with intractable non-malignant pain.].[在顽固性非恶性疼痛患者中使用可植入药物输送系统持续给予阿片类药物。]
Schmerz. 1991 Mar;5(1):28-36. doi: 10.1007/BF02529662.
3
Treatment challenges and complications with ziconotide monotherapy in established pump patients.
已植入泵的患者使用齐考诺肽单一疗法的治疗挑战和并发症
Pain Physician. 2006 Apr;9(2):147-52.
4
Treatment of spasticity with intrathecal Baclofen administration: long-term follow-up, review of 40 patients.鞘内注射巴氯芬治疗痉挛:40例患者的长期随访回顾
Spinal Cord. 2004 Dec;42(12):686-93. doi: 10.1038/sj.sc.3101647.
5
Treatment of infections associated with surgical implants.与外科植入物相关感染的治疗。
N Engl J Med. 2004 Apr 1;350(14):1422-9. doi: 10.1056/NEJMra035415.
6
[Pain therapy near the spinal marrow. Status survey in Germany and Austria].[脊髓附近的疼痛治疗。德国和奥地利的现状调查]
Schmerz. 1999 Apr 14;13(2):127-32. doi: 10.1007/s004829900032.
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Treatment of chronic pain by using intrathecal drug therapy compared with conventional pain therapies: a cost-effectiveness analysis.与传统疼痛疗法相比,鞘内药物疗法治疗慢性疼痛的成本效益分析。
J Neurosurg. 2002 Oct;97(4):803-10. doi: 10.3171/jns.2002.97.4.0803.
8
Functional benefits and cost/benefit analysis of continuous intrathecal baclofen infusion for the management of severe spasticity.鞘内持续注射巴氯芬治疗严重痉挛的功能效益及成本效益分析
J Neurosurg. 2002 Jun;96(6):1052-7. doi: 10.3171/jns.2002.96.6.1052.
9
Abrupt withdrawal from intrathecal baclofen: recognition and management of a potentially life-threatening syndrome.鞘内注射巴氯芬突然停药:一种潜在危及生命综合征的识别与处理
Arch Phys Med Rehabil. 2002 Jun;83(6):735-41. doi: 10.1053/apmr.2002.32820.
10
Outcome of intrathecal opioids in chronic non-cancer pain.鞘内注射阿片类药物治疗慢性非癌性疼痛的疗效
Eur J Pain. 2001;5(4):353-61. doi: 10.1053/eujp.2001.0255.