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对505例患者进行的前瞻性系列研究中腹腔镜治疗胆总管结石的评估:适应证与结果

Evaluation of laparoscopic treatment of common bile duct stones in a prospective series of 505 patients: indications and results.

作者信息

Berthou J Ch, Dron B, Charbonneau Ph, Moussalier K, Pellissier L

机构信息

Department of Digestive Surgery, Clinique chirurgicale mutualiste, 56107, Lorient Cedex, France.

出版信息

Surg Endosc. 2007 Nov;21(11):1970-4. doi: 10.1007/s00464-007-9387-5. Epub 2007 May 24.

DOI:10.1007/s00464-007-9387-5
PMID:17522929
Abstract

BACKGROUND

The aim of this prospective study was the evaluation of the laparoscopic treatment of common bile duct stones (CBDS) and its indications.

METHODS

Five hundred five patients who underwent laparoscopic treatment of CBDS from October 1990 to September 2006 were included in the prospective study. The mean age of the patients was 63 years (range = 19-93). Four hundred fifteen patients were classified ASA I and ASA II and 90 were ASA III and ASA IV. CBDS were suspected or diagnosed preoperatively in 373 patients (73.8%) and diagnosed at intraoperative cholangiography (IOC) in 132 patients (26.2%). A transcystic duct extraction (TCDE) was attempted in 254 patients (50.4%) and a primary choledochotomy in 251 patients (49.6%). Biliary drainage after choledochotomy was used in 148 cases (48.8%).

RESULTS

TCDE was successful in 191 cases (75.2%). The 63 failures were managed by laparoscopic choledochotomy in 53 cases and by endoscopic sphincterotomy (ES) in 10 cases. A choledochotomy was thus performed in 304 patients and successful in 295 cases (97%). The nine failures were managed by six conversions to laparotomy (2%) and three postoperative ES. The overall success rate was 96.2%. The morbidity rate was 7.9% with 4.8% of local complications and 3.1% of general complications. The mortality rate was 1%. There were 14 residual stones (2.8%) that were managed by a second laparoscopy in two cases and by ES in 12 cases with four failures managed by laparotomy in one case and laparoscopy in three cases.

CONCLUSION

Laparoscopic management of CBDS was effective in more than 96% of cases and particularly safe in ASA I and ASA II patients. It has the advantage over ES followed by laparoscopic cholecystectomy (LS) to be a one-stage procedure.

摘要

背景

本前瞻性研究旨在评估腹腔镜治疗胆总管结石(CBDS)及其适应证。

方法

1990年10月至2006年9月期间接受腹腔镜治疗CBDS的505例患者纳入本前瞻性研究。患者的平均年龄为63岁(范围=19 - 93岁)。415例患者分类为ASA I和ASA II级,90例为ASA III和ASA IV级。373例患者(73.8%)术前怀疑或诊断为CBDS,132例患者(26.2%)在术中胆管造影(IOC)时诊断为CBDS。254例患者(50.4%)尝试经胆囊管取石(TCDE),251例患者(49.6%)进行一期胆总管切开术。胆总管切开术后胆管引流148例(48.8%)。

结果

TCDE成功191例(75.2%)。63例失败病例中,53例通过腹腔镜胆总管切开术处理,10例通过内镜括约肌切开术(ES)处理。因此,304例患者进行了胆总管切开术,295例成功(97%)。9例失败病例中,6例转为开腹手术(2%),3例术后行ES。总体成功率为96.2%。发病率为7.9%,局部并发症为4.8%,全身并发症为3.1%。死亡率为1%。有14例残留结石(2.8%),2例通过二次腹腔镜手术处理,12例通过ES处理,4例失败病例中,1例通过开腹手术,3例通过腹腔镜手术处理。

结论

腹腔镜治疗CBDS在超过96%的病例中有效,尤其在ASA I和ASA II级患者中安全。与ES联合腹腔镜胆囊切除术(LS)相比,它具有一期手术的优势。

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