Wiltbank Thomas B, Giordano Gerald F
United Blood Services, Arizona Region, Scottsdale, Arizona, USA.
Transfusion. 2007 Jun;47(6):1002-5. doi: 10.1111/j.1537-2995.2007.01224.x.
Recent technology allows for the collection of 2-unit red cells (RBCs) and single-unit RBCs plus plasma or platelets (PLTs).
With a common definition of adverse events, 1,023,682 whole-blood collections were evaluated and compared with 249,154 two-unit apheresis RBC collections, 40,870 single-apheresis RBC collections, and 90,082 apheresis PLT collections.
The data show that manual whole-blood collections have a low incidence of moderate and severe reactions (47.1 per 10,000 collections, 0.47%). Single-unit RBCs collected by apheresis have the same safety profile (37.44 per 10,000 collections, p > 0.20). Double-RBC collections by apheresis and plateletpheresis have a significantly lower reaction rate (15.65 per 10,000 collections, p < 0.00005; and 14.84 per 10,000 collections, p < 0.00005, respectively).
It is concluded that automated collections are safe or safer than manual whole-blood collections. There should be few concerns when procedures are performed according to manufacturer's instructions.
近期技术允许采集2单位红细胞（RBC）以及单单位红细胞加血浆或血小板（PLT）。
采用不良事件的通用定义，对1,023,682次全血采集进行评估，并与249,154次双单位单采红细胞采集、40,870次单采红细胞采集以及90,082次单采血小板采集进行比较。
数据显示，手工全血采集的中度和重度反应发生率较低（每10,000次采集47.1例，0.47%）。单采的单单位红细胞具有相同的安全性（每10,000次采集37.44例，p>0.20）。双单位单采红细胞和单采血小板的反应率显著更低（分别为每10,000次采集15.65例，p<0.00005；以及每10,000次采集14.84例，p<0.00005）。
得出的结论是，自动化采集比手工全血采集更安全或至少同样安全。按照制造商的说明进行操作时，应无需过多担忧。
