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本文引用的文献

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Phosphatidylserine exposure on stored red blood cells as a parameter for donor-dependent variation in product quality.储存红细胞上磷脂酰丝氨酸的暴露作为产品质量中供体依赖性变异的一个参数。
Blood Transfus. 2014 Apr;12(2):204-9. doi: 10.2450/2013.0106-13. Epub 2013 Oct 3.
2
[Demography and donation frequencies of blood and plasma donor populations in Germany. Update 2010 and 5-year comparison].[德国血液和血浆捐献者群体的人口统计学及捐献频率。2010年更新及5年比较]
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Aug;55(8):914-22. doi: 10.1007/s00103-012-1515-2.
3
[HIV, HCV, HBV and syphilis surveillance among blood donors in Germany 2008-2010].[2008 - 2010年德国献血者中艾滋病毒、丙型肝炎病毒、乙型肝炎病毒和梅毒监测]
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Aug;55(8):907-13. doi: 10.1007/s00103-012-1516-1.
4
Sufficient blood, safe blood: can we have both?充足的血液,安全的血液:我们能否两者兼得?
BMC Med. 2012 Mar 23;10:29. doi: 10.1186/1741-7015-10-29.
5
Safety and frequency of whole blood donations from elderly donors.老年献血者全血捐献的安全性和频率。
Vox Sang. 2012 Feb;102(2):134-9. doi: 10.1111/j.1423-0410.2011.01531.x. Epub 2011 Aug 1.
6
Fresh frozen plasma quality: relation to age and gender of blood donors.新鲜冷冻血浆质量:与献血者年龄和性别有关。
Vox Sang. 2012 Feb;102(2):116-24. doi: 10.1111/j.1423-0410.2011.01518.x. Epub 2011 Jul 14.
7
The safety of blood donation by elderly blood donors.老年人献血的安全性。
Vox Sang. 2011 Nov;101(4):313-9. doi: 10.1111/j.1423-0410.2011.01492.x. Epub 2011 May 3.
8
Demographic Changes: The Impact for Safe Blood Supply.人口结构变化:对安全血液供应的影响。
Transfus Med Hemother. 2010 Jun;37(3):141-148. doi: 10.1159/000313949. Epub 2010 May 20.
9
Adverse reactions to allogeneic whole blood donation by 16- and 17-year-olds.16和17岁青少年异体全血捐献的不良反应。
JAMA. 2008 May 21;299(19):2279-86. doi: 10.1001/jama.299.19.2279.
10
Evidence-based criteria for the care and selection of blood donors, with some comments on the relationship to blood supply, and emphasis on the management of donation-induced iron depletion.献血者护理和选择的循证标准,对与血液供应关系的一些评论,并强调献血引起的铁缺乏的管理。
Transfus Med. 2008 Feb;18(1):13-27. doi: 10.1111/j.1365-3148.2007.00818.x.

老年重复献血者献血。

Blood donation by elderly repeat blood donors.

机构信息

DRK-Blutspendedienst West gGmbH, Zentrum für Transfusionsmedizin Breitscheid, Ratingen, Germany.

DRK-Blutspendedienst West gGmbH, Zentrum für Transfusionsmedizin Bad Kreuznach, Bad Kreuznach, Germany.

出版信息

Transfus Med Hemother. 2014 Jul;41(4):242-50. doi: 10.1159/000365401. Epub 2014 Jul 4.

DOI:10.1159/000365401
PMID:25254019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4164071/
Abstract

BACKGROUND

Upper age limits for blood donors are intended to protect elderly blood donors from donor reactions. However, due to a lack of data about adverse reactions in elderly blood donors, upper age limits are arbitrary and vary considerably between different countries.

METHODS

Here we present data from 171,231 voluntary repeat whole blood donors beyond the age of 68 years.

RESULTS

Blood donations from repeat blood donors beyond the age of 68 years increased from 2,114 in 2005 to 38,432 in 2012 (from 0,2% to 4.2% of all whole blood donations). Adverse donor reactions in repeat donors decreased with age and were lower than in the whole group (0.26%), even in donors older than 71 years (0.16%). However, from the age of 68 years, the time to complete recovery after donor reactions increased. Donor deferrals were highest in young blood donors (21.4%), but increased again in elderly blood donors beyond 71 years (12.6%).

CONCLUSION

Blood donation by regular repeat blood donors older than 71 years may be safely continued. However, due to a lack of data for donors older than 75 years, blood donation in these donors should be handled with great caution.

摘要

背景

设定献血者的最高年龄限制旨在保护老年献血者免受献血反应的影响。然而,由于缺乏关于老年献血者不良反应的数据,最高年龄限制是任意的,在不同国家之间差异很大。

方法

在这里,我们提供了 171231 名超过 68 岁的自愿重复全血献血者的数据。

结果

超过 68 岁的重复献血者的献血量从 2005 年的 2114 人增加到 2012 年的 38432 人(从所有全血献血量的 0.2%增加到 4.2%)。重复献血者的献血不良反应随着年龄的增长而减少,且低于总体水平(0.26%),即使是在年龄超过 71 岁的献血者中(0.16%)也是如此。然而,自 68 岁起,献血反应后完全恢复所需的时间增加。年轻献血者的献血延期率最高(21.4%),但 71 岁以上的老年献血者再次增加(12.6%)。

结论

定期重复献血超过 71 岁的献血者可以安全地继续献血。然而,由于缺乏 75 岁以上献血者的数据,这些献血者的献血应谨慎处理。