Nag D K, Petes T D
Department of Biology, University of North Carolina, Chapel Hill 27599-3280.
Genetics. 1991 Nov;129(3):669-73. doi: 10.1093/genetics/129.3.669.
Palindromic sequences in single-stranded DNA and RNA have the potential for intrastrand base pairing, resulting in formation of "hairpin" structures. We previously reported a genetic method for detecting such structures in vivo in the yeast Saccharomyces cerevisiae. Below, we describe evidence indicating that a 14-base-pair palindrome (7 bp per inverted repeat) is sufficient for formation of a hairpin in vivo.
单链DNA和RNA中的回文序列具有链内碱基配对的潜力,可导致“发夹”结构的形成。我们之前报道了一种在酿酒酵母体内检测此类结构的遗传学方法。下面,我们描述了相关证据,表明一个14个碱基对的回文序列(每个反向重复序列7个碱基对)足以在体内形成发夹结构。