tau，酵母中的一段重复DNA序列。
tau, a repeated DNA sequence in yeast.
作者信息
Chisholm G E, Genbauffe F S, Cooper T G
出版信息
Proc Natl Acad Sci U S A. 1984 May;81(10):2965-9. doi: 10.1073/pnas.81.10.2965.
Abstract
We have found a 371-base-pair (bp) repeated DNA element, tau, in Saccharomyces cerevisiae. The ends of tau are composed of a 5-bp inverted repeat, similar in sequence to those reported for the Ty, sigma, copia, and spleen necrosis virus elements. These inverted repeats are flanked by 5-bp direct repeats of a target sequence that occurs only once in an allele that lacks the tau element. This overall structure is characteristic of transposable elements. Like sigma, tau elements have been found (in both orientations) closely associated with tRNA genes (409 and 198 bp from the 5' end, respectively). It is noteworthy that one representative of tau was isolated in a concentric insertion of tau, delta, and sigma.
摘要
我们在酿酒酵母中发现了一个371个碱基对（bp）的重复DNA元件tau。tau的末端由一个5个碱基对的反向重复序列组成，其序列与报道的Ty、sigma、copia和脾坏死病毒元件的序列相似。这些反向重复序列两侧是靶序列的5个碱基对直接重复序列，该靶序列在缺乏tau元件的等位基因中仅出现一次。这种整体结构是转座元件的特征。与sigma一样，已发现tau元件（两种方向均有）与tRNA基因紧密相关（分别距离5'端409和198 bp）。值得注意的是，在tau、delta和sigma的同心插入中分离出了一个tau代表序列。
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Proc Natl Acad Sci U S A. 1984 May;81(10):2965-9. doi: 10.1073/pnas.81.10.2965.
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