1990年至2005年收集的肺炎克雷伯菌和肠杆菌属临床分离株中qnr流行率和氟喹诺酮耐药性的变化。
Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 to 2005.
作者信息
Strahilevitz Jacob, Engelstein Dalia, Adler Amos, Temper Violeta, Moses Allon E, Block Colin, Robicsek Ari
机构信息
Department of Clinical Microbiology and Infectious Diseases, Hadassah Ein-Kerem, Jerusalem, Israel.
出版信息
Antimicrob Agents Chemother. 2007 Aug;51(8):3001-3. doi: 10.1128/AAC.00256-07. Epub 2007 May 25.
Abstract
Clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 through 2005 at a tertiary care center were studied for qnr genes. Isolates bearing these genes emerged in the mid-1990s, coinciding with the time of a rapid increase in fluoroquinolone resistance. Sixty percent of these isolates were ciprofloxacin susceptible by CLSI breakpoints.
摘要
对1990年至2005年期间在一家三级医疗中心收集的肺炎克雷伯菌和肠杆菌属的临床分离株进行了qnr基因研究。携带这些基因的分离株出现在20世纪90年代中期，这与氟喹诺酮耐药性迅速增加的时间相吻合。根据CLSI标准，这些分离株中有60%对环丙沙星敏感。
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2
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4
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6
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