Robicsek A, Strahilevitz J, Sahm D F, Jacoby G A, Hooper D C
Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114-2696, USA.
Antimicrob Agents Chemother. 2006 Aug;50(8):2872-4. doi: 10.1128/AAC.01647-05.
We screened 313 ceftazidime-resistant Enterobacteriaceae isolates obtained in the United States from 1999 to 2004 for all three known qnr genes. A qnr gene was present in 20% of Klebsiella pneumoniae isolates, 31% of Enterobacter sp. isolates, and 4% of Escherichia coli isolates. qnrA and qnrB occurred with equivalent frequencies and, except for qnrB in enterobacters, were stable over time. qnrS was absent.
我们对1999年至2004年在美国获得的313株耐头孢他啶肠杆菌科分离株进行了全部三种已知qnr基因的筛查。qnr基因存在于20%的肺炎克雷伯菌分离株、31%的肠杆菌属分离株和4%的大肠杆菌分离株中。qnrA和qnrB出现的频率相当,除了肠杆菌中的qnrB外,随时间推移保持稳定。未检测到qnrS。