Ray M, Kothur K, Padhy S K, Saran P
Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Pediatr. 2007 May;74(5):492-4. doi: 10.1007/s12098-007-0084-0.
Hashimoto's encephalopathy is an under-recognized cause of acute encephalopathy both in children and adults. We hereby describe a 12.5 yr old boy with this rare disorder that presented with an acute onset of episodic psychosis with hallucinations along with seizures and had elevated antithyroid antibodies. Symptoms improved with thyroxine replacement and anticonvulsants and EEG normalized 3 mth into follow up. Hashimoto's encephalopathy should be considered in patients with unexplained encephalopathy and seizures, as prompt recognition and management can lead to an excellent outcome.
桥本脑病是儿童和成人急性脑病中一种未被充分认识的病因。我们在此描述一名12.5岁患有这种罕见疾病的男孩，他急性起病，伴有幻觉的发作性精神病以及癫痫发作，且抗甲状腺抗体升高。症状通过甲状腺素替代治疗和抗惊厥药物得到改善，随访3个月时脑电图恢复正常。对于患有不明原因脑病和癫痫发作的患者应考虑桥本脑病，因为及时识别和治疗可带来良好预后。
