McCombs Kathryn, Chen Suephy C
Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Dermatol Ther. 2007 Mar-Apr;20(2):102-9. doi: 10.1111/j.1529-8019.2007.00118.x.
Patient quality of life (QOL) is an important aspect of health care. It is crucial that we continue to develop instruments to assist in detecting burden of disease, interpreting outcomes of clinical trials, determining cost effectiveness of therapies, and guiding clinical decision making. The measurement of patient preferences, specifically utilities and contingent valuation, for health states provides data that can assist in the aforementioned endeavors. Patient preferences have been measured in many areas of medicine. However, it is relatively new to the field of dermatology. The present authors provide an overview of the basic concepts of patient preference measures and how they compare to the widely used health status instruments. Various techniques that have been used to elicit patient preferences are discussed, including standard gamble, time trade-off, willingness-to-pay, rating scales, health utilities index, and EuroQol (EQ-5D). In addition, the present authors review the current literature reporting utilities relevant to dermatology.
患者生活质量(QOL)是医疗保健的一个重要方面。我们继续开发工具以协助检测疾病负担、解读临床试验结果、确定治疗的成本效益以及指导临床决策,这至关重要。对健康状态下患者偏好的测量,特别是效用和条件价值评估,提供的数据有助于上述工作。患者偏好在医学的许多领域都已得到测量。然而,在皮肤科领域它相对较新。本文作者概述了患者偏好测量的基本概念以及它们与广泛使用的健康状况工具的比较。讨论了用于引出患者偏好的各种技术,包括标准博弈、时间权衡、支付意愿、评级量表、健康效用指数和欧洲生活质量五维度量表(EQ - 5D)。此外,本文作者回顾了当前报告与皮肤科相关效用的文献。