Li Chun-Shun, Di Ying-Tong, He Hong-Ping, Gao Suo, Wang Yue-Hu, Lu Yang, Zhong Jia-Liang, Hao Xiao-Jiang
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PRC.
Org Lett. 2007 Jun 21;9(13):2509-12. doi: 10.1021/ol070942+. Epub 2007 Jun 1.
Two novel alkaloids, daphlongeranines A (1) and B (2), with an unprecedented ring system, were isolated from the fruits of Daphniphyllum longeracemosum. Their unique structures and relative stereochemistries were established on the basis of spectroscopic and single-crystal diffraction analysis. The proposed biosynthetic pathway was also discussed. Compounds 1 and 2 showed weak inhibition on platelet aggregation.
从长序虎皮楠的果实中分离出两种具有前所未有的环系的新型生物碱——虎皮楠长碱A（1）和虎皮楠长碱B（2）。基于光谱和单晶衍射分析确定了它们独特的结构和相对立体化学。还讨论了推测的生物合成途径。化合物1和2对血小板聚集表现出微弱的抑制作用。
