Zeng Mingbing, Liu Yizhi, Liu Xialin, Yuan Zhaohui, Luo Lixia, Xia Yuanlin, Zeng Yangfa
Zhongshan Ophthalmic Center, Sun-Yat-Sen University, State Key Laboratory of Opthalmology, and The Second Affiliated Hospital, Guanzhou Medical College, Guangzhou, China.
Clin Exp Ophthalmol. 2007 May-Jun;35(4):355-60. doi: 10.1111/j.1442-9071.2007.01452.x.
Higher-order aberrations and contrast sensitivity were evaluated in patients who underwent phacoemulsification cataract extraction followed by implantation of aspherical, monofocal or multifocal intraocular lens (IOL) replacements.
In this comparative trial, 124 patients with an average age of 66.8+/-5.2 years and their 124 eyes were randomly divided into three surgical implantation groups to receive one of three types of IOLs in replacement of cataract lenses. The patients of group 1 were given an aspherical IOL Z9001 (AMO, Santa Ana, CA, USA) replacement, and group 2 was implanted a monofocal IOL SA60AT (Alcon, Fort Worth, TX, USA) and group 3 the multifocal IOL SA40N (AMO). Post-surgical best-corrected visual acuity, corneal aberrations, total ocular aberrations, pupil diameters, capsulorhexsis sizes and contrast sensitivity were measured and compared.
There was no statistical difference for mean best-corrected visual acuity, pupil diameter, curvilinear capsulorhexis size and corneal aberration among the three groups. For the spherical aberration, fourth-order higher-order aberration and total ocular higher-order aberration, the SA40N group was higher than the SA60AT group and the SA60AT group was higher than the Z9001 group, and the differences between the three groups were statistically significant for these measurements. Contrast sensitivity was higher for the Z9001 group than the SA60AT group and the SA60AT group was higher than the SA40N group, and the difference was statistically significant in all the spatial frequencies of 3, 6, 12 and 18.
Although the multifocal IOL can provide near vision, it can increase higher-order aberration and negatively influence contrast sensitivity. However, the aspherical IOL can reduce aberration and improve contrast sensitivity as compared with the monofocal IOL.
对接受白内障超声乳化摘除术并植入非球面、单焦点或多焦点人工晶状体（IOL）置换的患者进行了高阶像差和对比敏感度评估。
在这项对比试验中，124例平均年龄为66.8±5.2岁的患者及其124只眼睛被随机分为三个手术植入组，接受三种类型IOL之一以置换白内障晶状体。第1组患者接受非球面IOL Z9001（美国加利福尼亚州圣安娜市AMO公司）置换，第2组植入单焦点IOL SA60AT（美国得克萨斯州沃思堡市爱尔康公司），第3组植入多焦点IOL SA40N（AMO公司）。测量并比较术后最佳矫正视力、角膜像差、总眼像差、瞳孔直径、连续环形撕囊大小和对比敏感度。
三组之间的平均最佳矫正视力、瞳孔直径、连续环形撕囊大小和角膜像差无统计学差异。对于球差、四阶高阶像差和总眼高阶像差，SA40N组高于SA60AT组，SA60AT组高于Z9001组，三组之间在这些测量值上的差异具有统计学意义。Z9001组的对比敏感度高于SA60AT组，SA60AT组高于SA40N组，在3、6、12和18的所有空间频率上差异均具有统计学意义。
尽管多焦点IOL可提供近视力，但它会增加高阶像差并对对比敏感度产生负面影响。然而，与单焦点IOL相比，非球面IOL可减少像差并提高对比敏感度。
