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阿尔及利亚 Jord. et Fourr. 地上部分精油的生物活性和化学成分:多炔衍生物的出现。

Biological Activities and Chemical Composition of Jord. et Fourr. Aerial Part Essential Oil from Algeria: Occurrence of Polyacetylene Derivatives.

机构信息

Laboratoire des Produits Naturels, Département de Biologie, Université Abou Bekr Belkaïd, Imama Tlemcen 13000, Algeria.

Université de Corse-CNRS, UMR 6134 SPE, Route des Sanguinaires, 20000 Ajaccio, France.

出版信息

Molecules. 2019 Jan 8;24(1):204. doi: 10.3390/molecules24010204.

Abstract

The chemical composition of 18 oil samples of isolated from aerial parts at full flowering, collected in three locations in eastern Algeria was determined by GC(RI), GC/MS and C-NMR analysis. The major components were: germacrene D, myrcene, spathulenol, α-bisabolol, β-pinene, 1,8-cineole, -chrysanthenol, capillene, santolina alcohol, camphor, terpinen-4-ol and lyratol. The chemical composition appeared homogeneous and characterized by the occurrence of four derivatives which exhibited a conjugated alkene dialkyne moiety. They were identified for the first time in an essential oil from The collective oil sample exhibited moderate antimicrobial and antioxidant activities whereas the anti-inflammatory activity presented a real potential. IC value of essential oil (0.065 ± 0.004 mg/mL) is 5-fold higher than IC value of NDGA used as positive control.

摘要

从阿尔及利亚东部三个地点收集的开花高峰期的空中部分的 18 个油样的化学成分,通过 GC(RI)、GC/MS 和 C-NMR 分析进行了测定。主要成分有:大根香叶烯 D、月桂烯、螺旋醇、α- 倍半水芹醇、β-蒎烯、1,8-桉叶素、- 菊醇、大根香叶烯、樟醇、松油烯-4-醇和紫胶醇。化学成分表现出均匀性,其特征在于存在四个显示共轭烯炔二烷基部分的衍生物。它们是首次在来自 的精油中被鉴定出来。 集体油样表现出适度的抗菌和抗氧化活性,而抗炎活性表现出真正的潜力。 精油的 IC 值(0.065 ± 0.004 mg/mL)是用作阳性对照的 NDGA 的 IC 值的 5 倍。

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