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环境烟草烟雾在哮喘的发生和发展中的作用。

The role of environmental tobacco smoke in the origins and progression of asthma.

作者信息

Thomson Neil C

机构信息

Department of Respiratory Medicine, Division of Immunology, Infection and Inflammation, Western Infirmary and University of Glasgow, Glasgow G11 6NT, UK.

出版信息

Curr Allergy Asthma Rep. 2007 Jul;7(4):303-9. doi: 10.1007/s11882-007-0045-8.

DOI:10.1007/s11882-007-0045-8
PMID:17547853
Abstract

Exposure to environmental tobacco smoke (ETS) is a major source of indoor air pollution and causes adverse effects on the respiratory health of individuals with asthma. At least one third of children and adults with asthma are exposed to ETS on a regular basis. There is convincing evidence for a causal relationship between exposure to ETS and development of asthma in children and in nonsmoking adults. Exposure to ETS also worsens asthma control in children and nonsmoking adults who have established asthma. The mechanism by which ETS causes these harmful effects is not established but may involve genetic predisposition, impairment of lung development, and altered lung inflammatory responses. Workplace smoking restrictions and reduced smoking in the home may lower the prevalence of asthma, improve asthma control, and reduce the use of medical services in both children and adults who are exposed to ETS.

摘要

接触环境烟草烟雾(ETS)是室内空气污染的主要来源,会对哮喘患者的呼吸道健康产生不利影响。至少三分之一的哮喘儿童和成人经常接触ETS。有确凿证据表明,接触ETS与儿童和不吸烟成年人哮喘的发生之间存在因果关系。接触ETS还会使已患哮喘的儿童和不吸烟成年人的哮喘控制情况恶化。ETS造成这些有害影响的机制尚未明确,但可能涉及遗传易感性、肺发育受损以及肺部炎症反应改变。工作场所吸烟限制和家庭中吸烟减少,可能会降低接触ETS的儿童和成人的哮喘患病率,改善哮喘控制情况,并减少医疗服务的使用。

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