Chen Li-Hua, Feng Yi, Xu De-Sheng
Center of Science and Technology, Shanghai University of Treditional Chinese Medicine, Shanghai 201203, China.
Zhongguo Zhong Yao Za Zhi. 2007 Mar;32(6):472-5.
Pellets are multiple-unit drug delivery system, which have good fluidity, release stability and uniformity. With preparation techniques and excipient materials gradually established, pellets play an important part in the development of sustained/controlled release drug delivery system. The recent advances in pellets including the release mechanism, preparation methods, excipients and the characteristics in vivo for the sustained/controlled release pellets in traditional Chinese medicine (TCM) were reviewed in order to provide the strategies and rational methods for further investigations and applications.