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重症监护病房治疗幸存者中创伤后应激障碍的患病率:一项系统综述

The prevalence of post traumatic stress disorder in survivors of ICU treatment: a systematic review.

作者信息

Griffiths John, Fortune Gillian, Barber Vicki, Young J Duncan

机构信息

The John Radcliffe Hospital, Intensive Care Society Trials Group, Kadoorie Centre, Headley Way, OX3 9DU, Headington, Oxford, UK.

出版信息

Intensive Care Med. 2007 Sep;33(9):1506-18. doi: 10.1007/s00134-007-0730-z. Epub 2007 Jun 9.

Abstract

OBJECTIVE

To determine the prevalence of post traumatic stress disorder in survivors of intensive care treatment.

DESIGN

Systematic literature review including Medline, Embase, CINAHL, PsycINFO and references from identified papers.

STUDY SELECTION

Studies determining the prevalence of PTSD in adult patients who had at least 24[Symbol: see text]h treatment on an intensive care unit. Independent duplicate data extraction. Study quality was evaluated in terms of study design and method and timing of PTSD assessment. DATA SYNTHESIS AND RESULTS: Of the 1472 citations identified, 30 studies meeting the selection criteria were reviewed. PTSD was diagnosed by standardised clinical interview alone in 2 studies. A self-report measure alone was used in 19 studies to measure PTSD symptomatology. The remaining 9 studies applied both standardised clinical interview and a self-report measure. The reported prevalence of PTSD was 0-64% when diagnosed by standardised clinical interview and 5-64% by self-report measure. PTSD assessments occurred 7 days to 8 years after intensive care discharge.

CONCLUSION

The true prevalence of PTSD and the optimum timing and method of PTSD assessment have not yet been determined in intensive care unit survivors. Deficiencies in design, methodology and reporting make interpretation and comparison of quoted prevalence rates difficult, and rigorous longitudinal studies are needed.

摘要

目的

确定重症监护治疗幸存者中创伤后应激障碍的患病率。

设计

系统文献综述,包括检索Medline、Embase、CINAHL、PsycINFO以及已识别论文的参考文献。

研究选择

确定在重症监护病房接受至少24小时治疗的成年患者中创伤后应激障碍患病率的研究。独立进行重复数据提取。根据研究设计、方法以及创伤后应激障碍评估的时间对研究质量进行评估。

数据综合与结果

在检索到的1472篇文献中,对30项符合选择标准的研究进行了综述。2项研究仅通过标准化临床访谈诊断创伤后应激障碍。19项研究仅使用自我报告测量法来评估创伤后应激障碍症状。其余9项研究同时应用了标准化临床访谈和自我报告测量法。通过标准化临床访谈诊断的创伤后应激障碍患病率为0%至64%,通过自我报告测量法诊断的患病率为5%至64%。创伤后应激障碍评估在重症监护出院后7天至8年进行。

结论

重症监护病房幸存者中创伤后应激障碍的真实患病率以及创伤后应激障碍评估的最佳时间和方法尚未确定。研究设计、方法和报告方面的缺陷使得对所引用患病率的解释和比较变得困难,因此需要进行严格的纵向研究。

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