Beillas P, Lee S W, Tashman S, Yang K H
LBMC, French National Institute for Transport and Safety Research, INRETS UCBLI UMR-T 9406, Bron, France.
Comput Methods Biomech Biomed Engin. 2007 Jun;10(3):209-21. doi: 10.1080/10255840701283988.
A generic finite element (FE) model of the lower limb was used to study the knee response in-vivo during a one-legged hop. The approach uses an explicit FE code and a combination of estimated muscle forces and measured three-dimensional tibio-femoral kinematics and ground reaction force as input to the FE model. The sensitivity of the simulated tibio-femoral response to variations of key geometric and material parameters was investigated by performing a total of 38 different simulations. The amplitudes of both kinematic and kinetic responses were affected by the change of these parameters. For the current approach, the results suggest that while cartilage mechanical and geometric properties are very important for the estimation of tibio-femoral cartilage pressure, they have limited effects on the overall kinematic response. The study may help to better define the relative importance of modeling parameters for the development of subject-specific models.
使用一个通用的下肢有限元（FE）模型来研究单腿跳跃过程中膝关节的体内反应。该方法使用显式有限元代码，并将估计的肌肉力与测量的三维胫股运动学和地面反作用力相结合作为有限元模型的输入。通过总共进行38种不同的模拟，研究了模拟的胫股反应对关键几何和材料参数变化的敏感性。运动学和动力学反应的幅度都受到这些参数变化的影响。对于当前的方法，结果表明，虽然软骨的力学和几何特性对于估计胫股软骨压力非常重要，但它们对整体运动学反应的影响有限。该研究可能有助于更好地确定建模参数对于开发个体特异性模型的相对重要性。
