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仍然是层云而非高积云:反对日期/派对中心区别的进一步证据。

Still stratus not altocumulus: further evidence against the date/party hub distinction.

作者信息

Batada Nizar N, Reguly Teresa, Breitkreutz Ashton, Boucher Lorrie, Breitkreutz Bobby-Joe, Hurst Laurence D, Tyers Mike

出版信息

PLoS Biol. 2007 Jun;5(6):e154. doi: 10.1371/journal.pbio.0050154.

DOI:10.1371/journal.pbio.0050154
PMID:17564494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1892831/
Abstract

Analysis of multi-validated protein interaction data reveals networks with greater interconnectivity than the more segregated structures seen in previously available data. To help visualize this, the authors draw comparisons between continuous stratus clouds and altocumulus clouds.

摘要

对多重验证的蛋白质相互作用数据的分析显示,与先前可得数据中更分散的结构相比,这些网络具有更高的互连性。为了便于直观理解这一点,作者将连续层云和高积云进行了比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/d7489f18f0bd/pbio.0050154.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/50a9c0db7d52/pbio.0050154.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/9bdd30fa7c56/pbio.0050154.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/d96e4f92cb08/pbio.0050154.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/d7489f18f0bd/pbio.0050154.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/50a9c0db7d52/pbio.0050154.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/9bdd30fa7c56/pbio.0050154.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/d96e4f92cb08/pbio.0050154.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db2/2685601/d7489f18f0bd/pbio.0050154.g004.jpg

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2
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PLoS Biol. 2006 Oct;4(10):e317. doi: 10.1371/journal.pbio.0040317.
3
Evolutionary and physiological importance of hub proteins.枢纽蛋白的进化和生理重要性。
阐明人类与致病菌之间种内和种间蛋白质-蛋白质相互作用的网络特征和进化属性。
Sci Rep. 2021 Jan 8;11(1):190. doi: 10.1038/s41598-020-80549-x.
4
A large accessory protein interactome is rewired across environments.大量的辅助蛋白互作网络在不同环境中被重新布线。
Elife. 2020 Sep 14;9:e62365. doi: 10.7554/eLife.62365.
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Dependency Between Protein-Protein Interactions and Protein Variability and Evolutionary Rates in Vertebrates: Observed Relationships and Stochastic Modeling.脊椎动物中蛋白质-蛋白质相互作用与蛋白质变异性和进化率之间的关系:观察到的关系和随机模型。
J Mol Evol. 2019 Jul;87(4-6):184-198. doi: 10.1007/s00239-019-09899-z. Epub 2019 Jul 13.
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