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粒细胞肉瘤:脊髓压迫症的一种罕见病因。

Granulocytic sarcoma: an unusual cause of spinal cord compression.

作者信息

Balleari Enrico, Panarello Serena, Capello Elisabetta, Grosso Marco, Passalia Caterina, Pitto Paola, Raggi Francesca, Roccatagliata Luca, Cabiddu Francesco, Ghio Riccardo

机构信息

Department of Internal Medicine, University of Genoa, Genoa, Italy.

出版信息

Int J Clin Oncol. 2007 Jun;12(3):234-7. doi: 10.1007/s10147-006-0645-7. Epub 2007 Jun 27.

Abstract

A 76-year old woman presented with a large inguino-crural mass, multiple abdominal lymphoadenopathies, and neurological signs of spinal cord compression, first diagnosed as large-cell non-Hodgkin lymphoma. At subsequent clinical workup, a diagnosis of granulocytic sarcoma with meningeal involvement was made. Unfortunately, despite receiving intensive care, shortly after induction chemotherapy, the patient died of acute pneumonia followed by acute respiratory distress syndrome. The case is discussed in the framework of the existing literature and to derive clinical practice recommendations for this rare condition.

摘要

一名76岁女性因腹股沟-股部巨大肿块、多处腹部淋巴结肿大以及脊髓压迫的神经学体征就诊,最初被诊断为大细胞非霍奇金淋巴瘤。在随后的临床检查中,确诊为伴有脑膜受累的粒细胞肉瘤。不幸的是,尽管接受了重症监护,但在诱导化疗后不久,患者死于急性肺炎,随后并发急性呼吸窘迫综合征。本文结合现有文献对该病例进行了讨论,并针对这种罕见疾病提出了临床实践建议。

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