Li C-Y, Yang R-Y, Lin Y-C, She Z-G, Zhou S-N
School of Chemistry and Chemical Engineering, Zhongshan University, 510275 Guangzhou, China.
J Asian Nat Prod Res. 2007 Apr-Aug;9(3-5):285-91. doi: 10.1080/10286020600727418.
A new nonadride derivative, ( - )-1-hydroxybyssochlamic acid (1) and the known ( - )-byssochlamic acid (2) were isolated from mangrove fungus (strain No. k38) collected from the South China Sea coast. The structure and relative configuration of 1 were elucidated by spectral data and X-ray diffraction analysis. Primary bioassays showed that 2 had medium cytotoxic activity against HEp-2 and HepG2 Cells, and 1 exhibited weak activity.
从中国南海沿岸采集的红树林真菌（菌株编号k38）中分离出一种新的壬内酯衍生物，（-）-1-羟基柄曲霉素（1）和已知的（-）-柄曲霉素（2）。通过光谱数据和X射线衍射分析阐明了1的结构和相对构型。初步生物活性测定表明，2对HEp-2和HepG2细胞具有中等细胞毒性活性，而1表现出较弱的活性。
