Coenraads Pieter-Jan
Dermatology Department, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
J Invest Dermatol. 2007 Jul;127(7):1568-70. doi: 10.1038/sj.jid.5700781.
Clinicians agree that hand eczema is multifactorial, although there are many uncertainties regarding causative factors. Atopic dermatitis is assumed to be a major risk factor, whereas the role of allergies is overestimated. Twin studies may shed light on the contribution of other endogenous, possibly genetic factors versus the role of exposure to environmental agents, with the latter being amenable to prevention and intervention.
临床医生一致认为手部湿疹是多因素导致的，尽管在致病因素方面存在许多不确定性。特应性皮炎被认为是一个主要风险因素，而过敏的作用则被高估了。双胞胎研究可能有助于揭示其他内源性因素（可能是遗传因素）与接触环境因素的作用，后者是可以预防和干预的。
