Targonski Paul V, Poland Gregory A
Department of Internal Medicine, Mayo Vaccine Research Group, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Cleve Clin J Med. 2007 Jun;74(6):401-6, 408-10, 413-4. doi: 10.3949/ccjm.74.6.401.
The US Centers for Disease Control and Prevention recommends vaccination against Streptococcus pneumoniae for all people age 65 and older and also for younger people at high risk. However, experts continue to debate the efficacy of the vaccine; most observational studies found it beneficial, while clinical trials were inconclusive as a group. Although pneumococcal vaccination may or may not protect against pneumonia or death from any cause, it does significantly decrease the risk of invasive pneumococcal disease and is worthwhile for this reason.
美国疾病控制与预防中心建议，所有65岁及以上的人群以及高危年轻人群接种肺炎链球菌疫苗。然而，专家们仍在争论该疫苗的有效性；大多数观察性研究发现它有益，而作为一个整体，临床试验的结果尚无定论。虽然肺炎球菌疫苗可能预防或无法预防肺炎或任何原因导致的死亡，但它确实能显著降低侵袭性肺炎球菌疾病的风险，因此是值得接种的。
