Metrebian N, Mott J, Carnwath Z, Carnwath T, Stimson G V, Sell L
Centre for Research on Drugs and Health Behaviour, Imperial College London, London, UK.
Eur Addict Res. 2007;13(3):144-7. doi: 10.1159/000101550.
In the UK, few doctors prescribe diamorphine for the treatment of opiate dependence to a small number of patients. A retrospective case note review of patients receiving diamorphine in 2000 was conducted in the UK to determine how and why these patients came to receive a prescription for diamorphine. Patient eligibility criteria were examined together with doctors' stated reasons for initiating a diamorphine (heroin) prescription. Two hundred and ten sets of patients' case notes were reviewed at 27 of the 42 (64%) drug clinics in England and Wales where diamorphine was prescribed by the doctor. There appeared to be a general consensus among the few doctors who had prescribed diamorphine that it was a treatment of last resort, for those with long histories of heroin use and injecting, and those who had not responded sufficiently well to previous other treatments. However, there was also a small number of patients initiated on diamorphine without ever having previously received opiate treatments and some because they were experiencing problems injecting methadone. This reflects the UK history of the individual doctor's clinical autonomy in deciding when diamorphine is appropriate and the previous lack of nationally agreed patient eligibility criteria.
在英国,很少有医生会给少数患者开二乙酰吗啡用于治疗阿片类药物依赖。英国对2000年接受二乙酰吗啡治疗的患者进行了一项回顾性病例记录审查,以确定这些患者是如何以及为何开始接受二乙酰吗啡处方的。审查了患者的资格标准以及医生开具二乙酰吗啡(海洛因)处方的既定理由。在英格兰和威尔士42家(64%)有医生开具二乙酰吗啡的戒毒诊所中的27家,对210套患者病例记录进行了审查。在开过二乙酰吗啡处方的少数医生中,似乎普遍达成了一种共识,即这是一种最后的治疗手段,适用于有长期海洛因使用和注射史、且对之前其他治疗反应不够充分的患者。然而,也有少数患者从未接受过阿片类药物治疗就开始使用二乙酰吗啡,还有一些患者是因为在注射美沙酮时遇到问题。这反映了英国医生在决定何时使用二乙酰吗啡方面的临床自主权历史,以及此前缺乏全国统一的患者资格标准。