Yin Junf, Wei Xiaoyi, Yang Gengliang
Laboratory of Analytical Chemistry for Life Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China.
Se Pu. 2007 Mar;25(2):142-9.
In the past years, comprehensive attention has been paid on the monolithic materials for high performance liquid chromatography ( HPLC ) and capillary electrochromatography ( CEC) , due to their superior porosity, good permeability, large surface area and high diffusion mass transfer. They are well suited for both small molecules and large biopolymers. Monolithic polymer based stationary phases are the continuous unitary porous structure prepared by in situ polymerization inside the column tube and, if necessary, the surface can be functionalized with various functional groups. This review summarizes the development in preparation and application of polymer monoliths, mainly according to the literature published from 2003 to 2006.
在过去几年中，由于整体材料具有优异的孔隙率、良好的渗透性、大的表面积和高扩散传质特性，因此受到了高效液相色谱（HPLC）和毛细管电色谱（CEC）的广泛关注。它们适用于小分子和大型生物聚合物。基于整体聚合物的固定相是通过在柱管内原位聚合制备的连续整体多孔结构，如有必要，其表面可用各种官能团进行功能化。本综述主要根据2003年至2006年发表的文献，总结了聚合物整体柱在制备和应用方面的进展。
