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胰腺再次手术:做还是不做——这是个问题。

Pancreatic redo procedures: to do or not to do -- this is the question.

作者信息

Seelig Matthias H, Chromik Ansgar M, Weyhe Dirk, Müller Christophe A, Belyaev Orlin, Mittelkötter Ulrich, Tannapfel Andrea, Uhl Waldemar

机构信息

Department of General Surgery, St Joseph Hospital, Ruhr-University Bochum, Gudrunstrasse 56, Bochum, Germany.

出版信息

J Gastrointest Surg. 2007 Sep;11(9):1175-82. doi: 10.1007/s11605-007-0159-2.

Abstract

BACKGROUND

Pancreatic redo procedures belong to the most difficult abdominal operations because of altered anatomy, significant adhesions, and the potential of recurrent disease. We report on our experience with 15 redo procedures among a series of 350 consecutive pancreatic operations.

PATIENT AND METHODS

From January 1, 2004 to May 31, 2006 a total of 350 patients underwent pancreatic surgery in our department. There were 15 patients identified who had pancreatic redo surgery for benign (14) or malignant (1) disease. Perioperative parameters and outcome of 15 patients undergoing redo surgery after pancreatic resections were evaluated.

RESULTS

Operative procedures included revision and redo of the pancreaticojejunostomy after resection of the pancreatic margin (6), completion pancreatectomy (3), conversion from duodenum-preserving pancreatic head resection to pylorus-preserving pancreaticoduodenectomy (3), classic pancreaticoduodenectomy after nonresective pancreatic surgery (1), redo of left-sided pancreatectomy (1), and classic pancreaticoduodenectomy after left-sided pancreatectomy (1). Histology revealed chronic pancreatitis in 14 and a mucinous adenocarcinoma of the pancreas in 1 patient. Median operative time was 335 min (235-615 min) and median intraoperative blood loss was 600 ml (300-2,800 ml). Median postoperative ICU stay was 20 h (4-113 h) and median postoperative hospital stay was 15 days (7-30 days). There was no perioperative mortality and morbidity was 33%.

CONCLUSION

Pancreatic redo surgery can be performed with low morbidity and mortality. Redo surgery has a defined spectrum of indications, but to achieve good results surgery may be performed at high-volume centers.

摘要

背景

由于解剖结构改变、严重粘连以及疾病复发的可能性,胰腺再次手术属于腹部最困难的手术之一。我们报告了在连续350例胰腺手术中进行15例再次手术的经验。

患者与方法

2004年1月1日至2006年5月31日,我院共有350例患者接受了胰腺手术。其中15例患者因良性疾病(14例)或恶性疾病(1例)接受了胰腺再次手术。对15例胰腺切除术后接受再次手术患者的围手术期参数及结果进行了评估。

结果

手术方式包括胰腺切缘切除后胰肠吻合口的修复与再次手术(6例)、全胰切除术(3例)、保留十二指肠的胰头切除术转为保留幽门的胰十二指肠切除术(3例)、非切除性胰腺手术后的经典胰十二指肠切除术(1例)、左侧胰腺切除术的再次手术(1例)以及左侧胰腺切除术后的经典胰十二指肠切除术(1例)。组织学检查显示14例为慢性胰腺炎,1例为胰腺黏液腺癌。中位手术时间为335分钟(235 - 至615分钟),中位术中失血量为600毫升(300 - 2800毫升)。术后入住重症监护病房的中位时间为20小时(4 - 113小时),术后住院中位时间为15天(7 - 30天)。围手术期无死亡病例,并发症发生率为33%。

结论

胰腺再次手术可以在低并发症和低死亡率的情况下进行。再次手术有明确的适应证范围,但要取得良好效果,手术可能需在大型中心进行。

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