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直流电对肾功能的影响。一项在猪身上进行的实验研究。

Effects of direct current on renal function. An experimental study in pigs.

作者信息

Kinn A C, Nordenström B E, Elbarouni J, Nilsson I

机构信息

Department of Urology, Karolinska Sjukhuset, Stockholm, Sweden.

出版信息

Urol Res. 1991;19(6):397-400. doi: 10.1007/BF00310159.

DOI:10.1007/BF00310159
PMID:1759335
Abstract

Electric current from an external source was introduced between electrodes operatively placed into the ureters and positioned in the renal pelves of 13 pigs. Urinary excretion via the cathodic kidney showed a marked increase. The renal plasma flow and glomerular filtration rate diminished with increasing voltage, but no significant difference was found between the cathodic and the anodic kidney. The fractional sodium excretion by the cathodic kidney was 80% higher, indicating that the electric current mainly affected tubular function. A possible clinical application for electric fields in the kidneys is discussed.

摘要

将外部电源的电流引入可操作地放置在13头猪输尿管中并位于肾盂的电极之间。通过阴极肾脏的尿液排泄显著增加。随着电压升高,肾血浆流量和肾小球滤过率降低,但阴极肾脏和阳极肾脏之间未发现显著差异。阴极肾脏的钠排泄分数高出80%,表明电流主要影响肾小管功能。文中讨论了电场在肾脏中的可能临床应用。

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本文引用的文献

1
A rapid method for the determination of para-aminohippuric acid in kidney function tests.一种用于肾功能测试中对氨基马尿酸测定的快速方法。
J Lab Clin Med. 1951 Jun;37(6):955-8.
2
A new method for the determination of inulin in plasma and urine.一种测定血浆和尿液中菊粉的新方法。
Clin Chim Acta. 1956 Sep-Oct;1(5):470-4. doi: 10.1016/0009-8981(56)90020-1.
3
Neurovascular activation requires conduction through vessels.神经血管激活需要通过血管进行传导。
Physiol Chem Phys Med NMR. 1989;21(4):249-55; discussion 255-6.
4
The action potential: an effect of fuel cell reactions in the synapse.动作电位:突触中燃料电池反应的一种效应。
Physiol Chem Phys Med NMR. 1989;21(4):265-78.
5
Slow and rapid electrical pulses in the caval vein at pain-evoked leg contraction in the rat.大鼠腿部因疼痛诱发收缩时腔静脉中的慢速和快速电脉冲。
Physiol Chem Phys Med NMR. 1989;21(4):257-64.