Schnoor Maike, Hedicke Jens, Dalhoff Klaus, Raspe Heiner, Schäfer Torsten
Institute of Social Medicine, Medical University Schleswig-Holstein, Campus Luebeck, Beckergrube 43-47, Luebeck, Germany.
J Infect. 2007 Sep;55(3):233-9. doi: 10.1016/j.jinf.2007.04.355. Epub 2007 Jun 27.
In Germany the estimation of a population based annual incidence of community acquired pneumonia (CAP) in adults has been referred to the denominator problem. To estimate a population based annual incidence of CAP in an urban German area we compared the incidence estimated on four different approaches.
We estimated the annual incidence on the basis of the covered population of sentinel practices from Luebeck participating in the German competence network CAPNETZ. We estimated the incidence on the basis of a population based survey, on the basis of the mortality and lethality in Luebeck, and on the basis of data of the regional Association of Statutory Health Insurance Physicians ("Kassenärztliche Vereinigung (KV) Schleswig-Holstein").
The annual incidence of CAP in Luebeck was 3.7/1000 inhabitants (95% confidence interval (CI) 2.4-5.5), 6.0/1000 inhabitants, 8.7/1000 inhabitants (95% CI 8.2-9.1), or 10.1/1000 inhabitants (95% CI 9.6-10.5) depending on the approach of estimation. According to this, in Germany we would expect 400,000-680,000 new CAP cases per year.
The true incidence of CAP in Luebeck might range between 3.7 and 10 per 1000 inhabitants. Comparisons with the rates in the literature are difficult due to the differences in the applied methods.
在德国，基于人群估算成人社区获得性肺炎（CAP）的年发病率存在分母问题。为了估算德国一个城市地区基于人群的CAP年发病率，我们比较了四种不同方法估算的发病率。
我们基于吕贝克参与德国CAPNETZ能力网络的哨点医疗机构覆盖人群估算年发病率。我们还基于人群调查、吕贝克的死亡率和致死率以及地区法定医疗保险医师协会（“石勒苏益格 - 荷尔斯泰因州医师协会（KV）”）的数据估算发病率。
根据估算方法的不同，吕贝克CAP的年发病率分别为3.7/1000居民（95%置信区间（CI）2.4 - 5.5）、6.0/1000居民、8.7/1000居民（95%CI 8.2 - 9.1）或10.1/1000居民（95%CI 9.6 - 10.5）。据此，在德国我们预计每年有400,000 - 680,000例新的CAP病例。
吕贝克CAP的实际发病率可能在每1000居民3.7至10例之间。由于应用方法的差异，很难与文献中的发病率进行比较。
